Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish
Members of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can “turn on” and “turn off” signals. Recent studies have shown that this superfamily of proteins ha...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/9/4991 |
| _version_ | 1797504422432997376 |
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| author | Ritesh Urade Yan-Hui Chiu Chien-Chih Chiu Chang-Yi Wu |
| author_facet | Ritesh Urade Yan-Hui Chiu Chien-Chih Chiu Chang-Yi Wu |
| author_sort | Ritesh Urade |
| collection | DOAJ |
| description | Members of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can “turn on” and “turn off” signals. Recent studies have shown that this superfamily of proteins has various roles in the process of vascular development, such as vasculogenesis and angiogenesis. Here, we discuss the role of these subfamilies in the development of the vascular system in zebrafish. |
| first_indexed | 2024-03-10T04:05:22Z |
| format | Article |
| id | doaj.art-69233f177f194efd9945d2517a9a062c |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T04:05:22Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-69233f177f194efd9945d2517a9a062c2023-11-23T08:25:16ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-04-01239499110.3390/ijms23094991Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in ZebrafishRitesh Urade0Yan-Hui Chiu1Chien-Chih Chiu2Chang-Yi Wu3Department of Biological Sciences, National Sun Yat-sen University, Kaohsiung 804, TaiwanDepartment of Biological Sciences, National Sun Yat-sen University, Kaohsiung 804, TaiwanDepartment of Biological Sciences, National Sun Yat-sen University, Kaohsiung 804, TaiwanDepartment of Biological Sciences, National Sun Yat-sen University, Kaohsiung 804, TaiwanMembers of the Ras superfamily have been found to perform several functions leading to the development of eukaryotes. These small GTPases are divided into five major subfamilies, and their regulators can “turn on” and “turn off” signals. Recent studies have shown that this superfamily of proteins has various roles in the process of vascular development, such as vasculogenesis and angiogenesis. Here, we discuss the role of these subfamilies in the development of the vascular system in zebrafish.https://www.mdpi.com/1422-0067/23/9/4991small GTPasesGTP-binding proteinsvascular development and zebrafish |
| spellingShingle | Ritesh Urade Yan-Hui Chiu Chien-Chih Chiu Chang-Yi Wu Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish International Journal of Molecular Sciences small GTPases GTP-binding proteins vascular development and zebrafish |
| title | Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish |
| title_full | Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish |
| title_fullStr | Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish |
| title_full_unstemmed | Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish |
| title_short | Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish |
| title_sort | small gtpases and their regulators a leading road toward blood vessel development in zebrafish |
| topic | small GTPases GTP-binding proteins vascular development and zebrafish |
| url | https://www.mdpi.com/1422-0067/23/9/4991 |
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