The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients
One of the most common cancer malignancies is non-Hodgkin lymphoma, whose incidence is nearly 3% of all 36 cancers combined. It is the fourth highest cancer occurrence in children and accounts for 7% of cancers in patients under 20 years of age. Today, the survivability of individuals diagnosed with...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/14/6/1569 |
| _version_ | 1797446896120233984 |
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| author | Justyna Derebas Kinga Panuciak Mikołaj Margas Joanna Zawitkowska Monika Lejman |
| author_facet | Justyna Derebas Kinga Panuciak Mikołaj Margas Joanna Zawitkowska Monika Lejman |
| author_sort | Justyna Derebas |
| collection | DOAJ |
| description | One of the most common cancer malignancies is non-Hodgkin lymphoma, whose incidence is nearly 3% of all 36 cancers combined. It is the fourth highest cancer occurrence in children and accounts for 7% of cancers in patients under 20 years of age. Today, the survivability of individuals diagnosed with non-Hodgkin lymphoma varies by about 70%. Chemotherapy, radiation, stem cell transplantation, and immunotherapy have been the main methods of treatment, which have improved outcomes for many oncological patients. However, there is still the need for creation of novel medications for those who are treatment resistant. Additionally, more effective drugs are necessary. This review gathers the latest findings on non-Hodgkin lymphoma treatment options for pediatric patients. Attention will be focused on the most prominent therapies such as monoclonal antibodies, antibody–drug conjugates, chimeric antigen receptor T cell therapy and others. |
| first_indexed | 2024-03-09T13:47:12Z |
| format | Article |
| id | doaj.art-6929f3187b6247ba9ff1d04a3e384100 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T13:47:12Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-6929f3187b6247ba9ff1d04a3e3841002023-11-30T20:57:15ZengMDPI AGCancers2072-66942022-03-01146156910.3390/cancers14061569The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric PatientsJustyna Derebas0Kinga Panuciak1Mikołaj Margas2Joanna Zawitkowska3Monika Lejman4Student Scientific Society, Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Racławickie 1, 20-059 Lublin, PolandStudent Scientific Society, Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Racławickie 1, 20-059 Lublin, PolandStudent Scientific Society, Laboratory of Genetic Diagnostics, Medical University of Lublin, A. Racławickie 1, 20-059 Lublin, PolandDepartment Hematology, Oncology and Transplantology, Medical University of Lublin, A. Racławickie 1, 20-059 Lublin, PolandLaboratory of Genetic Diagnostics, Medical University of Lublin, A. Raclawickie 1, 20-059 Lublin, PolandOne of the most common cancer malignancies is non-Hodgkin lymphoma, whose incidence is nearly 3% of all 36 cancers combined. It is the fourth highest cancer occurrence in children and accounts for 7% of cancers in patients under 20 years of age. Today, the survivability of individuals diagnosed with non-Hodgkin lymphoma varies by about 70%. Chemotherapy, radiation, stem cell transplantation, and immunotherapy have been the main methods of treatment, which have improved outcomes for many oncological patients. However, there is still the need for creation of novel medications for those who are treatment resistant. Additionally, more effective drugs are necessary. This review gathers the latest findings on non-Hodgkin lymphoma treatment options for pediatric patients. Attention will be focused on the most prominent therapies such as monoclonal antibodies, antibody–drug conjugates, chimeric antigen receptor T cell therapy and others.https://www.mdpi.com/2072-6694/14/6/1569non-Hodgkin lymphomachildren and adolescentsaggressive non-Hodgkin lymphoma |
| spellingShingle | Justyna Derebas Kinga Panuciak Mikołaj Margas Joanna Zawitkowska Monika Lejman The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients Cancers non-Hodgkin lymphoma children and adolescents aggressive non-Hodgkin lymphoma |
| title | The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients |
| title_full | The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients |
| title_fullStr | The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients |
| title_full_unstemmed | The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients |
| title_short | The New Treatment Methods for Non-Hodgkin Lymphoma in Pediatric Patients |
| title_sort | new treatment methods for non hodgkin lymphoma in pediatric patients |
| topic | non-Hodgkin lymphoma children and adolescents aggressive non-Hodgkin lymphoma |
| url | https://www.mdpi.com/2072-6694/14/6/1569 |
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