Safety and Pharmacokinetics of the Substance of the Anti-Smallpox Drug NIOCH-14 after Oral Administration to Laboratory Animals

Safety and Pharmacokinetics of the Substance of the Anti-Smallpox Drug NIOCH-14 after Oral Administration to Laboratory Animals

Background: Since most of the modern human population has no anti-smallpox immunity, it is extremely important to develop and implement effective drugs for the treatment of smallpox and other orthopoxvirus infections. The objective of this study is to determine the main characteristics of the chemic...

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Bibliographic Details
Main Authors: Larisa N. Shishkina, Oleg Yu. Mazurkov, Nikolai I. Bormotov, Maksim O. Skarnovich, Olga A. Serova, Natalia A. Mazurkova, Maria A. Skarnovich, Alexander A. Chernonosov, Boris A. Selivanov, Alexey Ya. Tikhonov, Svetlana G. Gamaley, Galina G. Shimina, Galina M. Sysoyeva, Oleg S. Taranov, Elena D. Danilenko, Alexander P. Agafonov, Rinat A. Maksyutov
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Viruses
Subjects:
orthopoxviruses
anti-smallpox drugs
NIOCH-14
safety
pharmacokinetics
Online Access:https://www.mdpi.com/1999-4915/15/1/205

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https://www.mdpi.com/1999-4915/15/1/205

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