FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis

FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis

Fibroblast growth factor 1 (FGF1) belongs to a family of growth factors involved in cellular growth and division. MicroRNA 16 (miR‐16) is a regulator of gene expression, which is dysregulated during liver injury and insult. However, the role of FGF1 in the progression of biliary proliferation, senes...

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Bibliographic Details
Main Authors: April O’Brien, Tianhao Zhou, Tori White, Abigail Medford, Lixian Chen, Konstantina Kyritsi, Nan Wu, Jonathan Childs, Danaleigh Stiles, Ludovica Ceci, Sanjukta Chakraborty, Burcin Ekser, Leonardo Baiocchi, Guido Carpino, Eugenio Gaudio, Chaodong Wu, Lindsey Kennedy, Heather Francis, Gianfranco Alpini, Shannon Glaser
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2022-07-01
Series:Hepatology Communications
Online Access:https://doi.org/10.1002/hep4.1909

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