Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats
The single-nucleotide polymorphisms (SNPs) of the growth hormone (GH) gene could be related to growth traits, particularly in farm animals. This study aimed to identify the SNPs of the <i>GH</i> gene (A781G and A1575G) in Black Bengal (BB) goats in Thailand. Seventy-seven BB goats of bot...
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MDPI AG
2024-03-01
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| author | Chollada Buranakarl Sumonwan Chamsuwan Sumpun Thammacharoen Panupat Ratchakom Natthaya Chuaypen |
| author_facet | Chollada Buranakarl Sumonwan Chamsuwan Sumpun Thammacharoen Panupat Ratchakom Natthaya Chuaypen |
| author_sort | Chollada Buranakarl |
| collection | DOAJ |
| description | The single-nucleotide polymorphisms (SNPs) of the growth hormone (GH) gene could be related to growth traits, particularly in farm animals. This study aimed to identify the SNPs of the <i>GH</i> gene (A781G and A1575G) in Black Bengal (BB) goats in Thailand. Seventy-seven BB goats of both sexes were recruited, and their genotypes were identified. Preweaning growth at birth (weight, W0; height, H0; length, L0; and chest girth, C0) and at 10 weeks postpartum (W10, H10, L10, and C10), including average daily gain (ADG) at 0–4 weeks (ADG0–4W), 4–8 weeks (ADG4–8W), and 8–12 weeks (ADG8–12W), was compared among the different genotypes in goats born from twin litter-size dams. The results showed one genotype, CC, for A1575G and three genotypes, AA, AB, and BB, for A781G. The AA gene had significantly higher W10 than AB (<i>p</i> < 0.05) and BB (<i>p</i> < 0.05). The AA had significantly higher L10 than AB (<i>p</i> < 0.05), while C10 was only higher in male goats (<i>p</i> < 0.01). The ADG4–8W of the AA genotype was significantly higher than the BB genotype (<i>p</i> < 0.01). We came to the conclusion that A781G is associated with growth traits during the preweaning period, while the AA genotype showed better performance than the other genotypes. |
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| last_indexed | 2024-04-24T18:37:43Z |
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| spelling | doaj.art-69309729500b493689303bbb3144bae52024-03-27T13:17:36ZengMDPI AGAnimals2076-26152024-03-0114683410.3390/ani14060834Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal GoatsChollada Buranakarl0Sumonwan Chamsuwan1Sumpun Thammacharoen2Panupat Ratchakom3Natthaya Chuaypen4Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Henri Dunant Rd., Pathumwan, Bangkok 10330, ThailandDepartment of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Henri Dunant Rd., Pathumwan, Bangkok 10330, ThailandDepartment of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Henri Dunant Rd., Pathumwan, Bangkok 10330, ThailandChiang Rai Provincial Livestock Office, Department of Livestock Development, Chiang Rai 57000, ThailandMetabolic Diseases in Gut and Urinary System Research Unit (MeDGURU), Department of Biochemistry, Faculty of Medicine, Chulalongkorn University, Henri Dunant Rd., Pathumwan, Bangkok 10330, ThailandThe single-nucleotide polymorphisms (SNPs) of the growth hormone (GH) gene could be related to growth traits, particularly in farm animals. This study aimed to identify the SNPs of the <i>GH</i> gene (A781G and A1575G) in Black Bengal (BB) goats in Thailand. Seventy-seven BB goats of both sexes were recruited, and their genotypes were identified. Preweaning growth at birth (weight, W0; height, H0; length, L0; and chest girth, C0) and at 10 weeks postpartum (W10, H10, L10, and C10), including average daily gain (ADG) at 0–4 weeks (ADG0–4W), 4–8 weeks (ADG4–8W), and 8–12 weeks (ADG8–12W), was compared among the different genotypes in goats born from twin litter-size dams. The results showed one genotype, CC, for A1575G and three genotypes, AA, AB, and BB, for A781G. The AA gene had significantly higher W10 than AB (<i>p</i> < 0.05) and BB (<i>p</i> < 0.05). The AA had significantly higher L10 than AB (<i>p</i> < 0.05), while C10 was only higher in male goats (<i>p</i> < 0.01). The ADG4–8W of the AA genotype was significantly higher than the BB genotype (<i>p</i> < 0.01). We came to the conclusion that A781G is associated with growth traits during the preweaning period, while the AA genotype showed better performance than the other genotypes.https://www.mdpi.com/2076-2615/14/6/834Black Bengal goatgrowth hormone genegrowth traitssingle-nucleotide polymorphism |
| spellingShingle | Chollada Buranakarl Sumonwan Chamsuwan Sumpun Thammacharoen Panupat Ratchakom Natthaya Chuaypen Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats Animals Black Bengal goat growth hormone gene growth traits single-nucleotide polymorphism |
| title | Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats |
| title_full | Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats |
| title_fullStr | Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats |
| title_full_unstemmed | Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats |
| title_short | Single-Nucleotide Polymorphisms of Growth Hormone Gene and Its Relationship with Growth Traits in Black Bengal Goats |
| title_sort | single nucleotide polymorphisms of growth hormone gene and its relationship with growth traits in black bengal goats |
| topic | Black Bengal goat growth hormone gene growth traits single-nucleotide polymorphism |
| url | https://www.mdpi.com/2076-2615/14/6/834 |
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