History-based action selection bias in posterior parietal cortex

Past outcomes modulate activity in a diverse set of brain regions however their precise influence on decisions is not known. Here the authors show that posterior parietal cortex neurons encode history-related signals between trials and optogenetic inactivation during this epoch disrupts the history...

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Main Authors: Eun Jung Hwang, Jeffrey E. Dahlen, Madan Mukundan, Takaki Komiyama
Format: Article
Language:English
Published: Nature Portfolio 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01356-z
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author Eun Jung Hwang
Jeffrey E. Dahlen
Madan Mukundan
Takaki Komiyama
author_facet Eun Jung Hwang
Jeffrey E. Dahlen
Madan Mukundan
Takaki Komiyama
author_sort Eun Jung Hwang
collection DOAJ
description Past outcomes modulate activity in a diverse set of brain regions however their precise influence on decisions is not known. Here the authors show that posterior parietal cortex neurons encode history-related signals between trials and optogenetic inactivation during this epoch disrupts the history dependence of choice.
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spelling doaj.art-6931bc349a2144ad8f937c425b650a042022-12-21T18:32:15ZengNature PortfolioNature Communications2041-17232017-11-018111410.1038/s41467-017-01356-zHistory-based action selection bias in posterior parietal cortexEun Jung Hwang0Jeffrey E. Dahlen1Madan Mukundan2Takaki Komiyama3Neurobiology Section, Center for Neural Circuits and Behavior, Department of Neurosciences, University of California, San DiegoNeurobiology Section, Center for Neural Circuits and Behavior, Department of Neurosciences, University of California, San DiegoNeurobiology Section, Center for Neural Circuits and Behavior, Department of Neurosciences, University of California, San DiegoNeurobiology Section, Center for Neural Circuits and Behavior, Department of Neurosciences, University of California, San DiegoPast outcomes modulate activity in a diverse set of brain regions however their precise influence on decisions is not known. Here the authors show that posterior parietal cortex neurons encode history-related signals between trials and optogenetic inactivation during this epoch disrupts the history dependence of choice.https://doi.org/10.1038/s41467-017-01356-z
spellingShingle Eun Jung Hwang
Jeffrey E. Dahlen
Madan Mukundan
Takaki Komiyama
History-based action selection bias in posterior parietal cortex
Nature Communications
title History-based action selection bias in posterior parietal cortex
title_full History-based action selection bias in posterior parietal cortex
title_fullStr History-based action selection bias in posterior parietal cortex
title_full_unstemmed History-based action selection bias in posterior parietal cortex
title_short History-based action selection bias in posterior parietal cortex
title_sort history based action selection bias in posterior parietal cortex
url https://doi.org/10.1038/s41467-017-01356-z
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AT jeffreyedahlen historybasedactionselectionbiasinposteriorparietalcortex
AT madanmukundan historybasedactionselectionbiasinposteriorparietalcortex
AT takakikomiyama historybasedactionselectionbiasinposteriorparietalcortex