Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles
The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds. In order to achieve efficient and selective C-H functionalization, electrochemical synthesis has attracted increasing attent...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fchem.2022.967501/full |
| _version_ | 1811340026088259584 |
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| author | Ya-Nan Li Bin Wang Ye-Kai Huang Jin-Song Hu Jia-Nan Sun |
| author_facet | Ya-Nan Li Bin Wang Ye-Kai Huang Jin-Song Hu Jia-Nan Sun |
| author_sort | Ya-Nan Li |
| collection | DOAJ |
| description | The C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds. In order to achieve efficient and selective C-H functionalization, electrochemical synthesis has attracted increasing attention. Because electrochemical anodic oxidation is ideal for replacing chemical reagents in C-H functionalization reactions. This mini-review summarizes the current knowledge and recent advances since 2017 in the synthetic utility of electrochemical transformations for the C-H functionalization of nitrogen-containing heterocycles. |
| first_indexed | 2024-04-13T18:36:11Z |
| format | Article |
| id | doaj.art-693275311c114c5887613e9aac87e555 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-13T18:36:11Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-693275311c114c5887613e9aac87e5552022-12-22T02:34:53ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462022-08-011010.3389/fchem.2022.967501967501Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocyclesYa-Nan Li0Bin Wang1Ye-Kai Huang2Jin-Song Hu3Jia-Nan Sun4School of Chemical Engineering, Anhui University of Science and Technology, Huainan, ChinaSchool of Chemical Engineering, Anhui University of Science and Technology, Huainan, ChinaSchool of Chemical Engineering, Anhui University of Science and Technology, Huainan, ChinaSchool of Chemical Engineering, Anhui University of Science and Technology, Huainan, ChinaSchool of Biomedical Engineering, Research and Engineering Center of Biomedical Materials, Anhui Medical University, Hefei, ChinaThe C-H functionalization of nitrogen-containing heterocycles has emerged as a powerful strategy for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds. In order to achieve efficient and selective C-H functionalization, electrochemical synthesis has attracted increasing attention. Because electrochemical anodic oxidation is ideal for replacing chemical reagents in C-H functionalization reactions. This mini-review summarizes the current knowledge and recent advances since 2017 in the synthetic utility of electrochemical transformations for the C-H functionalization of nitrogen-containing heterocycles.https://www.frontiersin.org/articles/10.3389/fchem.2022.967501/fullelectrochemicalC-H bond functionalizationnitrogen-containing heterocyclesoxidant-freemetal catalyst-free |
| spellingShingle | Ya-Nan Li Bin Wang Ye-Kai Huang Jin-Song Hu Jia-Nan Sun Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles Frontiers in Chemistry electrochemical C-H bond functionalization nitrogen-containing heterocycles oxidant-free metal catalyst-free |
| title | Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles |
| title_full | Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles |
| title_fullStr | Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles |
| title_full_unstemmed | Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles |
| title_short | Recent advances in metal catalyst- and oxidant-free electrochemical C-H bond functionalization of nitrogen-containing heterocycles |
| title_sort | recent advances in metal catalyst and oxidant free electrochemical c h bond functionalization of nitrogen containing heterocycles |
| topic | electrochemical C-H bond functionalization nitrogen-containing heterocycles oxidant-free metal catalyst-free |
| url | https://www.frontiersin.org/articles/10.3389/fchem.2022.967501/full |
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