Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria
Hepatitis B virus (HBV) continues to cause serious health problems in developing countries. Neonatal infection with HBV, which is often acquired during delivery, carries a high risk resulting in persistent infection. This research aims to detect the prevalence of Hepatitis B surface Antigen (HBsAg)...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2012-04-01
|
| Series: | Microbiology Research |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/mr/article/view/3800 |
| _version_ | 1819279594565402624 |
|---|---|
| author | James A. Ndako Georgebest ON. Echeonwu Obinna O. Nwankiti Emamuzou M. Onovoh Alloysius U. Jah Nathaniel N. Shidali Patrick A. Ikani |
| author_facet | James A. Ndako Georgebest ON. Echeonwu Obinna O. Nwankiti Emamuzou M. Onovoh Alloysius U. Jah Nathaniel N. Shidali Patrick A. Ikani |
| author_sort | James A. Ndako |
| collection | DOAJ |
| description | Hepatitis B virus (HBV) continues to cause serious health problems in developing countries. Neonatal infection with HBV, which is often acquired during delivery, carries a high risk resulting in persistent infection. This research aims to detect the prevalence of Hepatitis B surface Antigen (HBsAg) among pregnant women in our location of study. One hundred and eighty (180) sera samples were screened among pregnant women aged 13-49, using standard enzyme-linked immunosorbent assay (ELISA) method. Structured questionnaire were administered to the subjects to obtain demographic and other relevant data. Overall result showed that 31 (17.2%) were found to be positive for HBsAg among the total subjects screened. The highest prevalence was found among those aged 20-29 with 11 (6.1%) seropositivity (x2=7.902; P=0.048). Considering occupational distribution of volunteer subjects, a high prevalence of 12 (6.7%); P<0.05 was recorded among house wives, which shows a measure of significance compared to other women screened. Furthermore, based on various risk factors subjects with history of surgery and use of unsterilized sharp instruments recorded 15 (8.3%) prevalence (P=0.233; P>0.05). How ever, women in their second trimester of pregnancy recorded a higher prevalence of 23 (12.8%):(P=0.080; P<0.05). This study therefore emphasizes the public health importance of HBV among pregnant women and equally suggests that children born to women with Hepatitis B Virus, be closely monitored for infection beyond the one and the half years of age, this also calls for a proper enlightenment on the dangers posed by the virus, while a well designed vaccination schedule is advocated among the general population. |
| first_indexed | 2024-12-24T00:30:23Z |
| format | Article |
| id | doaj.art-69383ad65df04c58b6709ee5ee346141 |
| institution | Directory Open Access Journal |
| issn | 2036-7473 2036-7481 |
| language | English |
| last_indexed | 2024-12-24T00:30:23Z |
| publishDate | 2012-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microbiology Research |
| spelling | doaj.art-69383ad65df04c58b6709ee5ee3461412022-12-21T17:24:16ZengMDPI AGMicrobiology Research2036-74732036-74812012-04-0131e10e1010.4081/mr.2012.e102081Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, NigeriaJames A. Ndako0Georgebest ON. Echeonwu1Obinna O. Nwankiti2Emamuzou M. Onovoh3Alloysius U. Jah4Nathaniel N. Shidali5Patrick A. Ikani6Department of Virology, Federal College of Veterinary and Medical Laboratory Technology, VomDepartment of Virology, Federal College of Veterinary and Medical Laboratory Technology, VomNational Veterinary Research Institute, VomDepartment of Virology, Federal College of Veterinary and Medical Laboratory Technology, VomDepartment of Virology, Federal College of Veterinary and Medical Laboratory Technology, VomDepartment of Medical Laboratory Sciences, University of MaiduguriDepartment of Medical Laboratory Services, Family Health International, BauchiHepatitis B virus (HBV) continues to cause serious health problems in developing countries. Neonatal infection with HBV, which is often acquired during delivery, carries a high risk resulting in persistent infection. This research aims to detect the prevalence of Hepatitis B surface Antigen (HBsAg) among pregnant women in our location of study. One hundred and eighty (180) sera samples were screened among pregnant women aged 13-49, using standard enzyme-linked immunosorbent assay (ELISA) method. Structured questionnaire were administered to the subjects to obtain demographic and other relevant data. Overall result showed that 31 (17.2%) were found to be positive for HBsAg among the total subjects screened. The highest prevalence was found among those aged 20-29 with 11 (6.1%) seropositivity (x2=7.902; P=0.048). Considering occupational distribution of volunteer subjects, a high prevalence of 12 (6.7%); P<0.05 was recorded among house wives, which shows a measure of significance compared to other women screened. Furthermore, based on various risk factors subjects with history of surgery and use of unsterilized sharp instruments recorded 15 (8.3%) prevalence (P=0.233; P>0.05). How ever, women in their second trimester of pregnancy recorded a higher prevalence of 23 (12.8%):(P=0.080; P<0.05). This study therefore emphasizes the public health importance of HBV among pregnant women and equally suggests that children born to women with Hepatitis B Virus, be closely monitored for infection beyond the one and the half years of age, this also calls for a proper enlightenment on the dangers posed by the virus, while a well designed vaccination schedule is advocated among the general population.http://www.pagepress.org/journals/index.php/mr/article/view/3800Hepatitis B, pregnant women, antenatal |
| spellingShingle | James A. Ndako Georgebest ON. Echeonwu Obinna O. Nwankiti Emamuzou M. Onovoh Alloysius U. Jah Nathaniel N. Shidali Patrick A. Ikani Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria Microbiology Research Hepatitis B, pregnant women, antenatal |
| title | Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria |
| title_full | Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria |
| title_fullStr | Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria |
| title_full_unstemmed | Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria |
| title_short | Sero-survey of Hepatitis B surface antigen amongst pregnant women attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria |
| title_sort | sero survey of hepatitis b surface antigen amongst pregnant women attending infectious disease hospital bayara bauchi state nigeria |
| topic | Hepatitis B, pregnant women, antenatal |
| url | http://www.pagepress.org/journals/index.php/mr/article/view/3800 |
| work_keys_str_mv | AT jamesandako serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria AT georgebestonecheonwu serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria AT obinnaonwankiti serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria AT emamuzoumonovoh serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria AT alloysiusujah serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria AT nathanielnshidali serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria AT patrickaikani serosurveyofhepatitisbsurfaceantigenamongstpregnantwomenattendinginfectiousdiseasehospitalbayarabauchistatenigeria |