4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one
The facile synthesis of 4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one (4) was achieved by the Mn(OAc)3-mediated aerobic oxidation of 2,4-pentanedione or the direct reaction of Mn(acac)3 in AcOH-TFE at room temperature under a dried air stream.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-10-01
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| Series: | Molbank |
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| Online Access: | http://www.mdpi.com/1422-8599/2016/4/M913 |
| _version_ | 1811243319961845760 |
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| author | Chiaki Akazaki Shun Kawabata Hiroshi Nishino |
| author_facet | Chiaki Akazaki Shun Kawabata Hiroshi Nishino |
| author_sort | Chiaki Akazaki |
| collection | DOAJ |
| description | The facile synthesis of 4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one (4) was achieved by the Mn(OAc)3-mediated aerobic oxidation of 2,4-pentanedione or the direct reaction of Mn(acac)3 in AcOH-TFE at room temperature under a dried air stream. |
| first_indexed | 2024-04-12T14:05:23Z |
| format | Article |
| id | doaj.art-6938bdcc8ee9422db4ab396402582477 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-04-12T14:05:23Z |
| publishDate | 2016-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-6938bdcc8ee9422db4ab3964025824772022-12-22T03:30:05ZengMDPI AGMolbank1422-85992016-10-0120164M91310.3390/M913M9134-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-oneChiaki Akazaki0Shun Kawabata1Hiroshi Nishino2Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, Kurokami 2-39-1, Kumamoto 860-8555, JapanDepartment of Chemistry, Graduate School of Science and Technology, Kumamoto University, Kurokami 2-39-1, Kumamoto 860-8555, JapanDepartment of Chemistry, Kumamoto University, Kurokami 2-39-1, Kumamoto 860-8555, JapanThe facile synthesis of 4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one (4) was achieved by the Mn(OAc)3-mediated aerobic oxidation of 2,4-pentanedione or the direct reaction of Mn(acac)3 in AcOH-TFE at room temperature under a dried air stream.http://www.mdpi.com/1422-8599/2016/4/M9134-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-oneketo-hemiacetalMn(acac)3Mn(OAc)3aerobic oxidation2,4-pentanedionecyclic acetaltrifluoroethanol |
| spellingShingle | Chiaki Akazaki Shun Kawabata Hiroshi Nishino 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one Molbank 4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one keto-hemiacetal Mn(acac)3 Mn(OAc)3 aerobic oxidation 2,4-pentanedione cyclic acetal trifluoroethanol |
| title | 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one |
| title_full | 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one |
| title_fullStr | 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one |
| title_full_unstemmed | 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one |
| title_short | 4-Acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one |
| title_sort | 4 acetyl 2 hydroxy 2 5 dimethylfuran 3 2h one |
| topic | 4-acetyl-2-hydroxy-2,5-dimethylfuran-3(2H)-one keto-hemiacetal Mn(acac)3 Mn(OAc)3 aerobic oxidation 2,4-pentanedione cyclic acetal trifluoroethanol |
| url | http://www.mdpi.com/1422-8599/2016/4/M913 |
| work_keys_str_mv | AT chiakiakazaki 4acetyl2hydroxy25dimethylfuran32hone AT shunkawabata 4acetyl2hydroxy25dimethylfuran32hone AT hiroshinishino 4acetyl2hydroxy25dimethylfuran32hone |