| Summary: | <p>Abstract</p> <p>Background</p> <p>The soluble cell adhesion molecules and adipokines are elevated in patients with obesity, hypertension, type 2 diabetes mellitus, breast cancer and atherosclerosis<b>.</b></p> <p>Objective</p> <p>To investigate the relationship between anthropometric profile, dietary intake, lipid profile and fasting glycemia with serum levels of adipokines (adiponectin and PAI-1) and adhesion molecules (ICAM-1 and VCAM-1) in women without breast cancer undergoing routine mammographic screening.</p> <p>Design</p> <p>Transversal study.</p> <p>Subjects</p> <p>One hundred and forty-five women over 40-years old participated in this study.</p> <p>Results</p> <p>In 39.3% of cases the BMI was above 30 kg/m<sup>2</sup>; 46.9% had hypertension, 14.5% had type 2 Diabetes Mellitus, 31.7% had dyslipidemia and 88.3% presented a waist-to-hip ratio ≥ 0.8. A linear correlation was found between serum levels of PAI-1 and triglycerides, between serum levels of PAI-1 and WHR and between serum levels of VCAM-1 and BMI.</p> <p>Conclusion</p> <p>We found a high prevalence of obesity and metabolic syndrome. PAI-1 and VCAM-1 levels were correlated with clinical indicators of obesity and overweight.</p>
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