Next-Generation Sequencing Whole-Genome Analysis for Targeted Treatment Approach of Metastatic Bartholin Gland Adenocarcinoma: An Emblematic Case Report and Review of the Literature

Next-Generation Sequencing Whole-Genome Analysis for Targeted Treatment Approach of Metastatic Bartholin Gland Adenocarcinoma: An Emblematic Case Report and Review of the Literature

Bartholin gland adenocarcinoma (BGA) is extremely rare and is characterized by high rates of lymph-node recurrence and distant metastases. No effective palliative treatments are available for metastatic BGA; therefore, advanced BGA remains a challenge for gynecologic oncologists. Considering the rar...

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Bibliographic Details
Main Authors: Antonio Macciò, Clelia Donisi, Elisabetta Sanna, Giacomo Chiappe, Sonia Nemolato, Luca Melis, Sara Oppi, Brunella Mola, Clelia Madeddu
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Diagnostics
Subjects:
vulvar cancer
Bartholin gland adenocarcinoma
minimally invasive surgery
whole genomic sequencing
immunotherapy
mTOR inhibitors
Online Access:https://www.mdpi.com/2075-4418/11/11/2085

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