The Anti-Breast Cancer Activity of Dihydroartemisinin-5-methylisatin Hybrids Tethered via Different Carbon Spacers

The Anti-Breast Cancer Activity of Dihydroartemisinin-5-methylisatin Hybrids Tethered via Different Carbon Spacers

Sixteen dihydroartemisinin-5-methylisatin hybrids <b>6a–c</b> and <b>7a–m</b> tethered via different carbon spacers were assessed for their antiproliferative activity against MCF-7, MDA-MB-231, MCF-7/ADR and MDA-MB-231/ADR breast cancer cell lines as well as cytotoxicity towa...

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Bibliographic Details
Main Authors: Yanfen Yao, Hong Wang, Jing Xu, Feng Gao, Wei Cao
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
artemisinin
isatin
hybrid molecules
breast cancer
drug resistance
Online Access:https://www.mdpi.com/1420-3049/27/22/7994

Internet

https://www.mdpi.com/1420-3049/27/22/7994

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