Optimal trial design selection: a comparative analysis between two-arm and three-arm trials incorporating network meta-analysis for evaluating a new treatment
Abstract Background Planning the design of a new trial comparing two treatments already in a network of trials with an a-priori plan to estimate the effect size using a network meta-analysis increases power or reduces the sample size requirements. However, when the comparison of interest is between...
Main Authors: | Fangshu Ye, Chong Wang, Annette M. O’Connor |
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Format: | Article |
Language: | English |
Published: |
BMC
2023-11-01
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Series: | BMC Medical Research Methodology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12874-023-02089-y |
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