Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions

Abstract Diabetes and hypertension are a serious public health problem worldwide. In the last decades, prevalence of these two metabolic diseases has dramatically increased in the Middle East and North Africa region, especially in Tunisia. This study aimed to determine the prevalence of type 2 diabe...

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Main Authors: Nadia Kheriji, Thouraya Dakhlaoui, Wafa Kamoun Rebai, Sonia Maatoug, Mohamed Taher Thabet, Thouraya Mellah, Mehdi Mrad, Hajer Trabelsi, Manel Soltani, Maria Kabbage, Hichem Ben Hassine, Afef Hadj Salah Bahlous, Faten Mahjoub, Henda Jamoussi, Abdelmajid Abid, Sonia Abdelhak, Rym Kefi
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39197-0
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author Nadia Kheriji
Thouraya Dakhlaoui
Wafa Kamoun Rebai
Sonia Maatoug
Mohamed Taher Thabet
Thouraya Mellah
Mehdi Mrad
Hajer Trabelsi
Manel Soltani
Maria Kabbage
Hichem Ben Hassine
Afef Hadj Salah Bahlous
Faten Mahjoub
Henda Jamoussi
Abdelmajid Abid
Sonia Abdelhak
Rym Kefi
author_facet Nadia Kheriji
Thouraya Dakhlaoui
Wafa Kamoun Rebai
Sonia Maatoug
Mohamed Taher Thabet
Thouraya Mellah
Mehdi Mrad
Hajer Trabelsi
Manel Soltani
Maria Kabbage
Hichem Ben Hassine
Afef Hadj Salah Bahlous
Faten Mahjoub
Henda Jamoussi
Abdelmajid Abid
Sonia Abdelhak
Rym Kefi
author_sort Nadia Kheriji
collection DOAJ
description Abstract Diabetes and hypertension are a serious public health problem worldwide. In the last decades, prevalence of these two metabolic diseases has dramatically increased in the Middle East and North Africa region, especially in Tunisia. This study aimed to determine the prevalence of type 2 diabetes (T2D) and High Blood Pressure (HBP) in Zaghouan, a North-East region of Tunisia. To this end, an exploratory study with stratified random sampling of 420 participants has been carried out. Various data were collected. Blood samples and urine were drawn for biochemical assay. Then, all data were analyzed using the statistical R software. Results showed an alarming situation with an inter-regional difference in prevalence of obesity (50.0%, CI 95.0%), HBP (39.0%, CI 95.0%) and T2D (32.0%, CI 95.0%). This study allowed the discovery of 24, 17 and 2 new cases of T2D, HBP and T2D&HBP respectively. The association of some socio-economic factors and biochemical parameters with these chronic diseases has been highlighted. To conclude, the health situation in the governorate of Zaghouan requires urgent interventions to better manage the growing epidemic of non-communicable diseases (NCD) in the region. This study demonstrated the importance of engaging health policy makers in road mapping and implementing national NCD prevention programs.
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spelling doaj.art-69412dadefa24676af55703531bc28f22023-11-26T13:24:16ZengNature PortfolioScientific Reports2045-23222023-08-0113111010.1038/s41598-023-39197-0Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actionsNadia Kheriji0Thouraya Dakhlaoui1Wafa Kamoun Rebai2Sonia Maatoug3Mohamed Taher Thabet4Thouraya Mellah5Mehdi Mrad6Hajer Trabelsi7Manel Soltani8Maria Kabbage9Hichem Ben Hassine10Afef Hadj Salah Bahlous11Faten Mahjoub12Henda Jamoussi13Abdelmajid Abid14Sonia Abdelhak15Rym Kefi16Laboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de TunisRegional Association of Diabetics of Zaghouan-Regional Hospital of ZaghouanLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de TunisUniversity of Tunis El ManarRegional Association of Diabetics of Zaghouan-Regional Hospital of ZaghouanHigher School of Digital Economy (ESEN-UMA), University of ManoubaUniversity of Tunis El ManarLaboratory of Clinical Biochemistry and Hormonology, Institut Pasteur de TunisLaboratory of Clinical Biochemistry and Hormonology, Institut Pasteur de TunisLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de TunisUniversity of Tunis El ManarUniversity of Tunis El ManarUniversity of Tunis El ManarUniversity of Tunis El ManarLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de TunisLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de TunisLaboratory of Biomedical Genomics and Oncogenetics, Institut Pasteur de TunisAbstract Diabetes and hypertension are a serious public health problem worldwide. In the last decades, prevalence of these two metabolic diseases has dramatically increased in the Middle East and North Africa region, especially in Tunisia. This study aimed to determine the prevalence of type 2 diabetes (T2D) and High Blood Pressure (HBP) in Zaghouan, a North-East region of Tunisia. To this end, an exploratory study with stratified random sampling of 420 participants has been carried out. Various data were collected. Blood samples and urine were drawn for biochemical assay. Then, all data were analyzed using the statistical R software. Results showed an alarming situation with an inter-regional difference in prevalence of obesity (50.0%, CI 95.0%), HBP (39.0%, CI 95.0%) and T2D (32.0%, CI 95.0%). This study allowed the discovery of 24, 17 and 2 new cases of T2D, HBP and T2D&HBP respectively. The association of some socio-economic factors and biochemical parameters with these chronic diseases has been highlighted. To conclude, the health situation in the governorate of Zaghouan requires urgent interventions to better manage the growing epidemic of non-communicable diseases (NCD) in the region. This study demonstrated the importance of engaging health policy makers in road mapping and implementing national NCD prevention programs.https://doi.org/10.1038/s41598-023-39197-0
spellingShingle Nadia Kheriji
Thouraya Dakhlaoui
Wafa Kamoun Rebai
Sonia Maatoug
Mohamed Taher Thabet
Thouraya Mellah
Mehdi Mrad
Hajer Trabelsi
Manel Soltani
Maria Kabbage
Hichem Ben Hassine
Afef Hadj Salah Bahlous
Faten Mahjoub
Henda Jamoussi
Abdelmajid Abid
Sonia Abdelhak
Rym Kefi
Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions
Scientific Reports
title Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions
title_full Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions
title_fullStr Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions
title_full_unstemmed Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions
title_short Prevalence and risk factors of diabetes mellitus and hypertension in North East Tunisia calling for efficient and effective actions
title_sort prevalence and risk factors of diabetes mellitus and hypertension in north east tunisia calling for efficient and effective actions
url https://doi.org/10.1038/s41598-023-39197-0
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