Siz2 Prevents Ribosomal DNA Recombination by Modulating Levels of Tof2 in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

Siz2 Prevents Ribosomal DNA Recombination by Modulating Levels of Tof2 in <named-content content-type="genus-species">Saccharomyces cerevisiae</named-content>

ABSTRACT Ribosomal DNA (rDNA) recombination in budding yeast is regulated by multiple converging processes, including posttranslational modifications such as SUMOylation. In this study, we report that the absence of a SUMO E3 ligase, Siz2, results in increased unequal rDNA exchange. We show that Siz...

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Bibliographic Details
Main Authors: Neethu Maria Abraham, Kathirvel Ramalingam, Saketh Murthy, Krishnaveni Mishra
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSphere
Subjects:
rDNA recombination
Siz2
Ulp2
Fob1
Tof2
SUMOylation
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00713-19

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