Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle

Abstract Staphylococcus aureus is a predominant cause of chronic lung infections. While the airway environment is rich in highly sialylated mucins, the interaction of S. aureus with sialic acid is poorly characterized. Using S. aureus USA300 as well as clinical isolates, we demonstrate that quorum-s...

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Bibliographic Details
Main Authors: Xiongqi Ding, Catherine Robbe-Masselot, Xiali Fu, Renaud Léonard, Benjamin Marsac, Charlene J. G. Dauriat, Agathe Lepissier, Héloïse Rytter, Elodie Ramond, Marion Dupuis, Daniel Euphrasie, Iharilalao Dubail, Cécile Schimmich, Xiaoquan Qin, Jessica Parraga, Maria Leite-de-Moraes, Agnes Ferroni, Benoit Chassaing, Isabelle Sermet-Gaudelus, Alain Charbit, Mathieu Coureuil, Anne Jamet
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43863-2

Internet

https://doi.org/10.1038/s41467-023-43863-2

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