Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults

Arterial ischemic stroke (AIS) experienced at a young age is undoubtedly a serious medical problem. AIS very rarely occurs at a developmental age, whereas in young adults, it occurs with a higher frequency. The etiologic mechanisms of AIS occurring in childhood and adulthood differ. However, for bot...

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Main Authors: Beata Sarecka-Hujar, Ilona Kopyta
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/10/1/24
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author Beata Sarecka-Hujar
Ilona Kopyta
author_facet Beata Sarecka-Hujar
Ilona Kopyta
author_sort Beata Sarecka-Hujar
collection DOAJ
description Arterial ischemic stroke (AIS) experienced at a young age is undoubtedly a serious medical problem. AIS very rarely occurs at a developmental age, whereas in young adults, it occurs with a higher frequency. The etiologic mechanisms of AIS occurring in childhood and adulthood differ. However, for both age populations, neurological consequences of AIS, including post-stroke seizures, motor disability, and recurrence of the disease, are connected to many years of care, rehabilitation, and treatment. Recurrent stroke was observed to increase the risk of patients’ mortality. One of the confirmed risk factors for recurrent stroke in children is the presence of vasculopathies, especially Moyamoya disease and syndrome, and focal cerebral arteriopathy of childhood (FCA). FCA causes a 5-fold increase in the risk of recurrent stroke in comparison with idiopathic AIS. In turn, young adults with recurrent stroke were found to more often suffer from hypertension, diabetes mellitus, or peripheral artery disease than young patients with first-ever stroke. Some reports also indicate relationships between specific genetic polymorphisms and AIS recurrence in both age groups. The aim of the present literature review was to discuss available data regarding the risk factors for recurrent AIS in children and young adults.
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spelling doaj.art-694577df4d484f858fa6a0efc9506b282022-12-22T00:04:59ZengMDPI AGBrain Sciences2076-34252020-01-011012410.3390/brainsci10010024brainsci10010024Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young AdultsBeata Sarecka-Hujar0Ilona Kopyta1Department of Pharmaceutical Technology, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, 41-200 Sosnowiec, PolandDepartment of Paediatric Neurology, School of Medicine in Katowice, Medical University of Silesia in Katowice, 40-752 Katowice, PolandArterial ischemic stroke (AIS) experienced at a young age is undoubtedly a serious medical problem. AIS very rarely occurs at a developmental age, whereas in young adults, it occurs with a higher frequency. The etiologic mechanisms of AIS occurring in childhood and adulthood differ. However, for both age populations, neurological consequences of AIS, including post-stroke seizures, motor disability, and recurrence of the disease, are connected to many years of care, rehabilitation, and treatment. Recurrent stroke was observed to increase the risk of patients’ mortality. One of the confirmed risk factors for recurrent stroke in children is the presence of vasculopathies, especially Moyamoya disease and syndrome, and focal cerebral arteriopathy of childhood (FCA). FCA causes a 5-fold increase in the risk of recurrent stroke in comparison with idiopathic AIS. In turn, young adults with recurrent stroke were found to more often suffer from hypertension, diabetes mellitus, or peripheral artery disease than young patients with first-ever stroke. Some reports also indicate relationships between specific genetic polymorphisms and AIS recurrence in both age groups. The aim of the present literature review was to discuss available data regarding the risk factors for recurrent AIS in children and young adults.https://www.mdpi.com/2076-3425/10/1/24arterial ischemic stroke (ais)recurrent strokerecurrencechildrenyoung adultsrisk factors
spellingShingle Beata Sarecka-Hujar
Ilona Kopyta
Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults
Brain Sciences
arterial ischemic stroke (ais)
recurrent stroke
recurrence
children
young adults
risk factors
title Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults
title_full Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults
title_fullStr Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults
title_full_unstemmed Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults
title_short Risk Factors for Recurrent Arterial Ischemic Stroke in Children and Young Adults
title_sort risk factors for recurrent arterial ischemic stroke in children and young adults
topic arterial ischemic stroke (ais)
recurrent stroke
recurrence
children
young adults
risk factors
url https://www.mdpi.com/2076-3425/10/1/24
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