Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead
Lead (Pb) is one of the major heavy metals that are toxic to vertebrates and usually considered as environmental pollutants. ABCC4/MRP4 is an organic anion transporter that mediates cellular efflux of a wide range of exogenous and endogenous compounds such as cyclic nucleotides and anti-cancer drugs...
Main Authors: | Xing Lu, Yong Long, Xixi Li, Lang Zhang, Qing Li, Hua Wen, Shan Zhong, Zongbin Cui |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/4/2054 |
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