Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation

Brg1 Supports B Cell Proliferation and Germinal Center Formation Through Enhancer Activation

Activation and differentiation of B cells depend on extensive rewiring of gene expression networks through changes in chromatin structure and accessibility. The chromatin remodeling complex BAF with its catalytic subunit Brg1 was previously identified as an essential regulator of early B cell develo...

Full description

Bibliographic Details
Main Authors: Dominik Schmiedel, Hadas Hezroni, Amit Hamburg, Ziv Shulman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Brg1
BAF
SWI/SNF
chromatin remodeling
enhancer activation
B cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.705848/full

Similar Items

Similar Items