Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing
Because the relationship between Crohn’s Disease (CD) activity and CD-related fatigue remains poorly understood, this study investigated the role of underlying psychological processes (depression, anxiety, and emotional processing). It was expected that the relationship between CD activity and CD-re...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-04-01
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| Series: | Frontiers in Psychology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyg.2020.00703/full |
| _version_ | 1828498394433191936 |
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| author | Ingrid Banovic Louise Montreuil Marie Derrey-Bunel Fabrizio Scrima Guillaume Savoye Laurent Beaugerie Marie-Claire Gay |
| author_facet | Ingrid Banovic Louise Montreuil Marie Derrey-Bunel Fabrizio Scrima Guillaume Savoye Laurent Beaugerie Marie-Claire Gay |
| author_sort | Ingrid Banovic |
| collection | DOAJ |
| description | Because the relationship between Crohn’s Disease (CD) activity and CD-related fatigue remains poorly understood, this study investigated the role of underlying psychological processes (depression, anxiety, and emotional processing). It was expected that the relationship between CD activity and CD-related fatigue would be mediated by depression and anxiety and also by a deficit in emotional processing. This prediction was tested in 110 CD patients who completed self-reported questionnaires assessing fatigue (FSS), clinical activity of Crohn’s Disease (HBAI), psychological suffering (HADS), and emotional processing (EPS-25). A path analysis showed both direct and indirect effects in the relationship between CD activity and CD-related fatigue, accounting for 33% of the variance. One indirect effect on the experience of fatigue was depression, but there was no effect of anxiety. These preliminary results confirmed that disease activity induces an increase in depressive symptoms, which in turn leads to an increase in the level of fatigue. The most novel result of the present study is that emotional processing had an indirect effect on the relationship between CD and CD-related fatigue: when the disease was more active, patients exhibited greater disruption of emotional processing, which in turn led to greater fatigue. These results did not reveal any association between depression and emotional processing. In conclusion, this work highlights the role of emotional processing in CD-related fatigue and the importance of taking this factor into account in order to manage this condition better. |
| first_indexed | 2024-12-11T13:06:18Z |
| format | Article |
| id | doaj.art-6947b00375084dc9a3697cc9d0707265 |
| institution | Directory Open Access Journal |
| issn | 1664-1078 |
| language | English |
| last_indexed | 2024-12-11T13:06:18Z |
| publishDate | 2020-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychology |
| spelling | doaj.art-6947b00375084dc9a3697cc9d07072652022-12-22T01:06:19ZengFrontiers Media S.A.Frontiers in Psychology1664-10782020-04-011110.3389/fpsyg.2020.00703522406Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional ProcessingIngrid Banovic0Louise Montreuil1Marie Derrey-Bunel2Fabrizio Scrima3Guillaume Savoye4Laurent Beaugerie5Marie-Claire Gay6CRFDP (EA7475), Rouen Normandy University, UFR SHS, Mont-Saint-Aignan, FranceCRFDP (EA7475), Rouen Normandy University, UFR SHS, Mont-Saint-Aignan, FranceCRFDP (EA7475), Rouen Normandy University, Hôpital Jacques Monod, Montivilliers, FranceCRFDP (EA7475), Rouen Normandy University, UFR SHS, Mont-Saint-Aignan, FranceCHU Charles Nicolles, Rouen, FranceHôpital Saint-Antoine, Paris, FranceCLIPSYD (EA4430), Paris Nanterre University, Nanterre, FranceBecause the relationship between Crohn’s Disease (CD) activity and CD-related fatigue remains poorly understood, this study investigated the role of underlying psychological processes (depression, anxiety, and emotional processing). It was expected that the relationship between CD activity and CD-related fatigue would be mediated by depression and anxiety and also by a deficit in emotional processing. This prediction was tested in 110 CD patients who completed self-reported questionnaires assessing fatigue (FSS), clinical activity of Crohn’s Disease (HBAI), psychological suffering (HADS), and emotional processing (EPS-25). A path analysis showed both direct and indirect effects in the relationship between CD activity and CD-related fatigue, accounting for 33% of the variance. One indirect effect on the experience of fatigue was depression, but there was no effect of anxiety. These preliminary results confirmed that disease activity induces an increase in depressive symptoms, which in turn leads to an increase in the level of fatigue. The most novel result of the present study is that emotional processing had an indirect effect on the relationship between CD and CD-related fatigue: when the disease was more active, patients exhibited greater disruption of emotional processing, which in turn led to greater fatigue. These results did not reveal any association between depression and emotional processing. In conclusion, this work highlights the role of emotional processing in CD-related fatigue and the importance of taking this factor into account in order to manage this condition better.https://www.frontiersin.org/article/10.3389/fpsyg.2020.00703/fullfatigueCrohn’s Diseasedisease activityemotional processingdepressionanger |
| spellingShingle | Ingrid Banovic Louise Montreuil Marie Derrey-Bunel Fabrizio Scrima Guillaume Savoye Laurent Beaugerie Marie-Claire Gay Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing Frontiers in Psychology fatigue Crohn’s Disease disease activity emotional processing depression anger |
| title | Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing |
| title_full | Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing |
| title_fullStr | Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing |
| title_full_unstemmed | Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing |
| title_short | Toward Further Understanding of Crohn’s Disease-Related Fatigue: The Role of Depression and Emotional Processing |
| title_sort | toward further understanding of crohn s disease related fatigue the role of depression and emotional processing |
| topic | fatigue Crohn’s Disease disease activity emotional processing depression anger |
| url | https://www.frontiersin.org/article/10.3389/fpsyg.2020.00703/full |
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