Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer
Cervical cancer is one of the major cancer types, the leading causes of cancer-related deaths in women worldwide, with a significant socioeconomic burden. Metformin, an inexpensive, traditional oral anti-hyperglycemic drug, is one of the most widely used antidiabetic drug for type 2...
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| Format: | Article |
| Language: | English |
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The Royal Thai College of Obstetricians and Gynaecologists
2016-09-01
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| Series: | Thai Journal of Obstetrics and Gynaecology |
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| Online Access: | https://tci-thaijo.org/index.php/tjog/article/download/65283/pdf_1/ |
| _version_ | 1818272441781190656 |
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| author | Jitti Hanprasertpong |
| author_facet | Jitti Hanprasertpong |
| author_sort | Jitti Hanprasertpong |
| collection | DOAJ |
| description | Cervical cancer is one of the major cancer types, the leading causes of cancer-related deaths in women worldwide, with a significant socioeconomic burden. Metformin, an inexpensive, traditional oral anti-hyperglycemic drug, is one of the most widely used antidiabetic drug for type 2 diabetes mellitus. In recent years, there has been an increasing interest in the use of metformin to reduce cancer risk and improve oncological outcomes of various cancer types, including cervical cancer. The precise mechanism of the antitumor effect of metformin is still unclear. Herein I review the scientific evidence from preclinical and clinical studies on the antitumor effect of metformin on cancer risk and oncological outcomes of cervical cancer. |
| first_indexed | 2024-12-12T21:42:07Z |
| format | Article |
| id | doaj.art-694a0fccb21d4aacb2101103ab4b1757 |
| institution | Directory Open Access Journal |
| issn | 0857-6084 0857-6084 |
| language | English |
| last_indexed | 2024-12-12T21:42:07Z |
| publishDate | 2016-09-01 |
| publisher | The Royal Thai College of Obstetricians and Gynaecologists |
| record_format | Article |
| series | Thai Journal of Obstetrics and Gynaecology |
| spelling | doaj.art-694a0fccb21d4aacb2101103ab4b17572022-12-22T00:11:01ZengThe Royal Thai College of Obstetricians and GynaecologistsThai Journal of Obstetrics and Gynaecology0857-60840857-60842016-09-01243142144https://doi.org/10.14456/tjog.2016.24Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancerJitti Hanprasertpong0Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, ThailandCervical cancer is one of the major cancer types, the leading causes of cancer-related deaths in women worldwide, with a significant socioeconomic burden. Metformin, an inexpensive, traditional oral anti-hyperglycemic drug, is one of the most widely used antidiabetic drug for type 2 diabetes mellitus. In recent years, there has been an increasing interest in the use of metformin to reduce cancer risk and improve oncological outcomes of various cancer types, including cervical cancer. The precise mechanism of the antitumor effect of metformin is still unclear. Herein I review the scientific evidence from preclinical and clinical studies on the antitumor effect of metformin on cancer risk and oncological outcomes of cervical cancer.https://tci-thaijo.org/index.php/tjog/article/download/65283/pdf_1/cervical cancerdiabetes mellitusmetformin |
| spellingShingle | Jitti Hanprasertpong Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer Thai Journal of Obstetrics and Gynaecology cervical cancer diabetes mellitus metformin |
| title | Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer |
| title_full | Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer |
| title_fullStr | Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer |
| title_full_unstemmed | Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer |
| title_short | Metformin – a possible way to reduce risk and improve oncological outcome of cervical cancer |
| title_sort | metformin a possible way to reduce risk and improve oncological outcome of cervical cancer |
| topic | cervical cancer diabetes mellitus metformin |
| url | https://tci-thaijo.org/index.php/tjog/article/download/65283/pdf_1/ |
| work_keys_str_mv | AT jittihanprasertpong metforminapossiblewaytoreduceriskandimproveoncologicaloutcomeofcervicalcancer |