A Designed Experiments Approach to Optimizing MALDI-TOF MS Spectrum Processing Parameters Enhances Detection of Antibiotic Resistance in Campylobacter jejuni

A Designed Experiments Approach to Optimizing MALDI-TOF MS Spectrum Processing Parameters Enhances Detection of Antibiotic Resistance in Campylobacter jejuni

MALDI-TOF MS has been utilized as a reliable and rapid tool for microbial fingerprinting at the genus and species levels. Recently, there has been keen interest in using MALDI-TOF MS beyond the genus and species levels to rapidly identify antibiotic resistant strains of bacteria. The purpose of this...

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Bibliographic Details
Main Authors: Christian ePenny, Beau eGrothendick, Lin eZhang, Connie eBorror, Duane eBarbano, Angela eCornelius, Brent eGilpin, Clifton eFagerquist, William eZaragoza, Michele T. Jay-Russell, Albert eLastovica, Catherine eRagimbeau, Henry-Michel eCauchie, Todd eSandrin
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Microbiology
Subjects:
Campylobacter jejuni
antibiotic resistance
antimicrobial resistance
MALDI-TOF MS
Designed experiments
Spectrum processing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00818/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00818/full

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