Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway

Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway

Summary: Background: Inflammatory bowel disease (IBD) has complex genetic and environmental aspects, and free fatty acid receptors (FFARs) may bridge genetic and dietary aspects. FFAR4 is highly expressed in the intestine and acts primarily as the receptor of long-chain fatty acids, which are major...

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Bibliographic Details
Main Authors: Shenglong Zhu, Jingwei Zhang, Xuan Jiang, Wei Wang, Yong Q. Chen
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:EBioMedicine
Subjects:
FFAR4
Colitis
Treg
IL33
ZBED6
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422002419

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