Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization
Curcumin loaded octenylsuccinate fish scale gelatin (OFSG) was prepared in this study, to explore the potential of FSG for delivering hydrophobic nutrients. The effects of molecule weight (<i>M</i><sub>w</sub>, 22,677–369 g/mol) and degree of substitution (<i>DS</i&g...
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MDPI AG
2022-09-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/11/18/2911 |
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| author | Xiaoyan Yu Haoxin Li Aida Wan Mustapha Wan Tingyuan Ren Zunguo Lei Jia Liu |
| author_facet | Xiaoyan Yu Haoxin Li Aida Wan Mustapha Wan Tingyuan Ren Zunguo Lei Jia Liu |
| author_sort | Xiaoyan Yu |
| collection | DOAJ |
| description | Curcumin loaded octenylsuccinate fish scale gelatin (OFSG) was prepared in this study, to explore the potential of FSG for delivering hydrophobic nutrients. The effects of molecule weight (<i>M</i><sub>w</sub>, 22,677–369 g/mol) and degree of substitution (<i>DS</i>, 0–0.116) on the curcumin loading efficiency (CLE, μg/mL) of OFSG (6.98–26.85 mg/mL) were evaluated. The expose of interior hydrophobic groups in FSG and increased intermolecular hydrophobic area contributed to the loading of curcumin in two phases, respectively. The interaction between OFSG and curcumin showed a decreased absorption in FTIR and an increased crystallinity in XRD. The loading of curcumin into OFSG caused a significant decrease of the particle size (from 350–12,070 to 139–214 nm), PDI (from 0.584–0.659 to 0.248–0.347) and <i>ζ</i>-potential (−12.2 or −11.4 to −21.0 or −20.3). OFSG showed a significantly higher stability and lower release of curcumin than FSG at the end of the simulated gastrointestinal digestion. Thus, OFSG showed great potential in the construction of a carrier for hydrophobic nutrients. |
| first_indexed | 2024-03-10T00:01:19Z |
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| id | doaj.art-69512cd97cb94390874ff7ec1a62100d |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-10T00:01:19Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-69512cd97cb94390874ff7ec1a62100d2023-11-23T16:15:19ZengMDPI AGFoods2304-81582022-09-011118291110.3390/foods11182911Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and CharacterizationXiaoyan Yu0Haoxin Li1Aida Wan Mustapha Wan2Tingyuan Ren3Zunguo Lei4Jia Liu5School of Liquor & Food Engineering, Guizhou University, Guiyang 550025, ChinaThe Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, School of Public Health, Guizhou Medical University, Guiyang 550025, ChinaDepartment of Food Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia (UKM), Bangi 43600, MalaysiaSchool of Liquor & Food Engineering, Guizhou University, Guiyang 550025, ChinaInstitute of Food Processing Technology, Guizhou Academy of Agricultural Sciences, Guiyang 550006, ChinaSchool of Liquor & Food Engineering, Guizhou University, Guiyang 550025, ChinaCurcumin loaded octenylsuccinate fish scale gelatin (OFSG) was prepared in this study, to explore the potential of FSG for delivering hydrophobic nutrients. The effects of molecule weight (<i>M</i><sub>w</sub>, 22,677–369 g/mol) and degree of substitution (<i>DS</i>, 0–0.116) on the curcumin loading efficiency (CLE, μg/mL) of OFSG (6.98–26.85 mg/mL) were evaluated. The expose of interior hydrophobic groups in FSG and increased intermolecular hydrophobic area contributed to the loading of curcumin in two phases, respectively. The interaction between OFSG and curcumin showed a decreased absorption in FTIR and an increased crystallinity in XRD. The loading of curcumin into OFSG caused a significant decrease of the particle size (from 350–12,070 to 139–214 nm), PDI (from 0.584–0.659 to 0.248–0.347) and <i>ζ</i>-potential (−12.2 or −11.4 to −21.0 or −20.3). OFSG showed a significantly higher stability and lower release of curcumin than FSG at the end of the simulated gastrointestinal digestion. Thus, OFSG showed great potential in the construction of a carrier for hydrophobic nutrients.https://www.mdpi.com/2304-8158/11/18/2911curcuminfish scalehydrophobic interactionnano-assemblyoctenylsuccination |
| spellingShingle | Xiaoyan Yu Haoxin Li Aida Wan Mustapha Wan Tingyuan Ren Zunguo Lei Jia Liu Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization Foods curcumin fish scale hydrophobic interaction nano-assembly octenylsuccination |
| title | Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization |
| title_full | Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization |
| title_fullStr | Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization |
| title_full_unstemmed | Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization |
| title_short | Curcumin-Loaded Self-Assembly Constructed by Octenylsuccinate Fish (<i>Cyprinus carpio</i> L.) Scale Gelatin: Preparation and Characterization |
| title_sort | curcumin loaded self assembly constructed by octenylsuccinate fish i cyprinus carpio i l scale gelatin preparation and characterization |
| topic | curcumin fish scale hydrophobic interaction nano-assembly octenylsuccination |
| url | https://www.mdpi.com/2304-8158/11/18/2911 |
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