The role of μ-opioid receptors in the regulation of hepatic secretory function

Influence of intraperitoneal and intracerebroventricular DAGO (μ-opioid agonist) on the bile secretion and composition was studied in white rats having intact and denervated liver. DAGO was demostrated to alter bile composition significantly both intraperitoneally and intracerebroventricularly and t...

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Main Authors: M. A. Medvedev, I. V. Rudin, A. F. Garayeva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2006-06-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3070
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author M. A. Medvedev
I. V. Rudin
A. F. Garayeva
author_facet M. A. Medvedev
I. V. Rudin
A. F. Garayeva
author_sort M. A. Medvedev
collection DOAJ
description Influence of intraperitoneal and intracerebroventricular DAGO (μ-opioid agonist) on the bile secretion and composition was studied in white rats having intact and denervated liver. DAGO was demostrated to alter bile composition significantly both intraperitoneally and intracerebroventricularly and these effects were opposite. Intact liver innervation is a necessary condition for intracerebroventricular DAGO to have its effect on bile secretion.
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spelling doaj.art-6954823fdfe0429cbe27007959db08ab2023-03-13T09:58:05ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842006-06-0152909510.20538/1682-0363-2006-2-90-951728The role of μ-opioid receptors in the regulation of hepatic secretory functionM. A. Medvedev0I. V. Rudin1A. F. Garayeva2Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетInfluence of intraperitoneal and intracerebroventricular DAGO (μ-opioid agonist) on the bile secretion and composition was studied in white rats having intact and denervated liver. DAGO was demostrated to alter bile composition significantly both intraperitoneally and intracerebroventricularly and these effects were opposite. Intact liver innervation is a necessary condition for intracerebroventricular DAGO to have its effect on bile secretion.https://bulletin.ssmu.ru/jour/article/view/3070опиоидные пептидыdagoналоксонсекреция желчиopioid peptidesdagonaloxonesecretion of bile
spellingShingle M. A. Medvedev
I. V. Rudin
A. F. Garayeva
The role of μ-opioid receptors in the regulation of hepatic secretory function
Бюллетень сибирской медицины
опиоидные пептиды
dago
налоксон
секреция желчи
opioid peptides
dago
naloxone
secretion of bile
title The role of μ-opioid receptors in the regulation of hepatic secretory function
title_full The role of μ-opioid receptors in the regulation of hepatic secretory function
title_fullStr The role of μ-opioid receptors in the regulation of hepatic secretory function
title_full_unstemmed The role of μ-opioid receptors in the regulation of hepatic secretory function
title_short The role of μ-opioid receptors in the regulation of hepatic secretory function
title_sort role of μ opioid receptors in the regulation of hepatic secretory function
topic опиоидные пептиды
dago
налоксон
секреция желчи
opioid peptides
dago
naloxone
secretion of bile
url https://bulletin.ssmu.ru/jour/article/view/3070
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