Recent advancements in the use of exosomes as drug delivery systems
Abstract Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many st...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12951-018-0403-9 |
| _version_ | 1818038473778528256 |
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| author | Edwin J. Bunggulawa Wei Wang Tieying Yin Nan Wang Colm Durkan Yazhou Wang Guixue Wang |
| author_facet | Edwin J. Bunggulawa Wei Wang Tieying Yin Nan Wang Colm Durkan Yazhou Wang Guixue Wang |
| author_sort | Edwin J. Bunggulawa |
| collection | DOAJ |
| description | Abstract Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell. |
| first_indexed | 2024-12-10T07:43:18Z |
| format | Article |
| id | doaj.art-6955548c90b94d35ae1b6d6754857d0e |
| institution | Directory Open Access Journal |
| issn | 1477-3155 |
| language | English |
| last_indexed | 2024-12-10T07:43:18Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Nanobiotechnology |
| spelling | doaj.art-6955548c90b94d35ae1b6d6754857d0e2022-12-22T01:57:14ZengBMCJournal of Nanobiotechnology1477-31552018-10-0116111310.1186/s12951-018-0403-9Recent advancements in the use of exosomes as drug delivery systemsEdwin J. Bunggulawa0Wei Wang1Tieying Yin2Nan Wang3Colm Durkan4Yazhou Wang5Guixue Wang6Key Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing UniversityKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing UniversityKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing UniversityNanoscience Centre, Department of Engineering, University of CambridgeNanoscience Centre, Department of Engineering, University of CambridgeKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing UniversityKey Laboratory of Biorheological Science and Technology, Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, College of Bioengineering, Chongqing UniversityAbstract Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell.http://link.springer.com/article/10.1186/s12951-018-0403-9Extracellular vesiclesExosomeDelivery properties |
| spellingShingle | Edwin J. Bunggulawa Wei Wang Tieying Yin Nan Wang Colm Durkan Yazhou Wang Guixue Wang Recent advancements in the use of exosomes as drug delivery systems Journal of Nanobiotechnology Extracellular vesicles Exosome Delivery properties |
| title | Recent advancements in the use of exosomes as drug delivery systems |
| title_full | Recent advancements in the use of exosomes as drug delivery systems |
| title_fullStr | Recent advancements in the use of exosomes as drug delivery systems |
| title_full_unstemmed | Recent advancements in the use of exosomes as drug delivery systems |
| title_short | Recent advancements in the use of exosomes as drug delivery systems |
| title_sort | recent advancements in the use of exosomes as drug delivery systems |
| topic | Extracellular vesicles Exosome Delivery properties |
| url | http://link.springer.com/article/10.1186/s12951-018-0403-9 |
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