Atomic Force Microscopy Application in Biological Research: A Review Study
Atomic force microscopy (AFM) is a three-dimensional topographic technique with a high atomic resolution to measure surface roughness. AFM is a kind of scanning probe microscope, and its near-field technique is based on the interaction between a sharp tip and the atoms of the sample surface. There a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2013-06-01
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| Series: | Iranian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://ijms.sums.ac.ir/index.php/IJMS/article/view/281 |
| _version_ | 1811195138476605440 |
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| author | Surena Vahabi Bahareh Nazemi Salman Anahita Javanmard |
| author_facet | Surena Vahabi Bahareh Nazemi Salman Anahita Javanmard |
| author_sort | Surena Vahabi |
| collection | DOAJ |
| description | Atomic force microscopy (AFM) is a three-dimensional topographic technique with a high atomic resolution to measure surface roughness. AFM is a kind of scanning probe microscope, and its near-field technique is based on the interaction between a sharp tip and the atoms of the sample surface. There are several methods and many ways to modify the tip of the AFM to investigate surface properties, including measuring friction, adhesion forces and viscoelastic properties as well as determining the Young modulus and imaging magnetic or electrostatic properties. The AFM technique can analyze any kind of samples such as polymers, adsorbed molecules, films or fibers, and powders in the air whether in a controlled atmosphere or in a liquid medium. In the past decade, the AFM has emerged as a powerful tool to obtain the nanostructural details and biomechanical properties of biological samples, including biomolecules and cells. The AFM applications, techniques, and -in particular- its ability to measure forces, are not still familiar to most clinicians. This paper reviews the literature on the main principles of the AFM modality and highlights the advantages of this technique in biology, medicine, and- especially- dentistry. This literature review was performed through E-resources, including Science Direct, PubMed, Blackwell Synergy, Embase, Elsevier, and Scholar Google for the references published between 1985 and 2010. |
| first_indexed | 2024-04-12T00:37:25Z |
| format | Article |
| id | doaj.art-6959c139d08646eea382782c59d6ab4b |
| institution | Directory Open Access Journal |
| issn | 0253-0716 1735-3688 |
| language | English |
| last_indexed | 2024-04-12T00:37:25Z |
| publishDate | 2013-06-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Sciences |
| spelling | doaj.art-6959c139d08646eea382782c59d6ab4b2022-12-22T03:55:06ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882013-06-013827683Atomic Force Microscopy Application in Biological Research: A Review StudySurena VahabiBahareh Nazemi SalmanAnahita JavanmardAtomic force microscopy (AFM) is a three-dimensional topographic technique with a high atomic resolution to measure surface roughness. AFM is a kind of scanning probe microscope, and its near-field technique is based on the interaction between a sharp tip and the atoms of the sample surface. There are several methods and many ways to modify the tip of the AFM to investigate surface properties, including measuring friction, adhesion forces and viscoelastic properties as well as determining the Young modulus and imaging magnetic or electrostatic properties. The AFM technique can analyze any kind of samples such as polymers, adsorbed molecules, films or fibers, and powders in the air whether in a controlled atmosphere or in a liquid medium. In the past decade, the AFM has emerged as a powerful tool to obtain the nanostructural details and biomechanical properties of biological samples, including biomolecules and cells. The AFM applications, techniques, and -in particular- its ability to measure forces, are not still familiar to most clinicians. This paper reviews the literature on the main principles of the AFM modality and highlights the advantages of this technique in biology, medicine, and- especially- dentistry. This literature review was performed through E-resources, including Science Direct, PubMed, Blackwell Synergy, Embase, Elsevier, and Scholar Google for the references published between 1985 and 2010.http://ijms.sums.ac.ir/index.php/IJMS/article/view/281Atomic force microscopyScanning tunneling microscopyScanning probe microscopyDentalBiological |
| spellingShingle | Surena Vahabi Bahareh Nazemi Salman Anahita Javanmard Atomic Force Microscopy Application in Biological Research: A Review Study Iranian Journal of Medical Sciences Atomic force microscopy Scanning tunneling microscopy Scanning probe microscopy Dental Biological |
| title | Atomic Force Microscopy Application in Biological Research: A Review Study |
| title_full | Atomic Force Microscopy Application in Biological Research: A Review Study |
| title_fullStr | Atomic Force Microscopy Application in Biological Research: A Review Study |
| title_full_unstemmed | Atomic Force Microscopy Application in Biological Research: A Review Study |
| title_short | Atomic Force Microscopy Application in Biological Research: A Review Study |
| title_sort | atomic force microscopy application in biological research a review study |
| topic | Atomic force microscopy Scanning tunneling microscopy Scanning probe microscopy Dental Biological |
| url | http://ijms.sums.ac.ir/index.php/IJMS/article/view/281 |
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