Evaluation of [<sup>64</sup>Cu]Cu-NOTA-PEG<sub>7</sub>-H-Tz for Pretargeted Imaging in LS174T Xenografts—Comparison to [<sup>111</sup>In]In-DOTA-PEG<sub>11</sub>-BisPy-Tz

Evaluation of [<sup>64</sup>Cu]Cu-NOTA-PEG<sub>7</sub>-H-Tz for Pretargeted Imaging in LS174T Xenografts—Comparison to [<sup>111</sup>In]In-DOTA-PEG<sub>11</sub>-BisPy-Tz

Pretargeted nuclear imaging for the diagnosis of various cancers is an emerging and fast developing field. The tetrazine ligation is currently considered the most promising reaction in this respect. Monoclonal antibodies are often the preferred choice as pretargeting vector due to their outstanding...

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Bibliographic Details
Main Authors: Christian B. M. Poulie, Jesper T. Jørgensen, Vladimir Shalgunov, Georgios Kougioumtzoglou, Troels Elmer Jeppesen, Andreas Kjaer, Matthias M. Herth
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Molecules
Subjects:
tetrazine
pretargeted imaging
radiochemistry
PET
SPECT
cancer
Online Access:https://www.mdpi.com/1420-3049/26/3/544

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