The histopathology of culture proven Melioidosis

Context: Melioidosis is a bacterial infection with high morbidity and mortality. Published literature on histopatholgical findings of melioidosis is sparse. Aims: To describe the histopathological findings in melioidosis. Settings and design: This is a retrospective observational study conducted at...

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Main Authors: Rajeshwari K Muthusamy, Deepak Thangaraju, Sangita S Mehta, Lavanya P
Format: Article
Language:English
Published: National Board of Examinations 2023-12-01
Series:National Board of Examinations Journal of Medical Sciences
Subjects:
Online Access:https://natboard.edu.in/ejournal/articledtl?x=bGUvbFlzN2xUTjFPeUY0blVpcFY3Zz09
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author Rajeshwari K Muthusamy
Deepak Thangaraju
Sangita S Mehta
Lavanya P
author_facet Rajeshwari K Muthusamy
Deepak Thangaraju
Sangita S Mehta
Lavanya P
author_sort Rajeshwari K Muthusamy
collection DOAJ
description Context: Melioidosis is a bacterial infection with high morbidity and mortality. Published literature on histopatholgical findings of melioidosis is sparse. Aims: To describe the histopathological findings in melioidosis. Settings and design: This is a retrospective observational study conducted at a tertiary care center in south India. Materials and methods: Histopathological findings of tissue samples from which Burkholderia pseudomallei was isolated in culture were analysed. Statistical analysis: The quantitative variables were expressed as frequency. Results: Histopathological findings in melioidosis were either acute (12 out of 18 samples), acute on chronic (5 out of 18 samples) and chronic (1 out of 18 samples). Granuloma was noted in 5 samples. Conclusion: Any acute or acute on chronic inflammation with or without granuloma in tissues from patients in endemic regions should raise the suspicion of melioidosis.
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spelling doaj.art-695fa7e43e6f44128121e9e28843b2a22023-12-17T11:23:15ZengNational Board of ExaminationsNational Board of Examinations Journal of Medical Sciences2583-75242023-12-01Volume 11275175910.61770/NBEJMS.2023.v01.i12.005The histopathology of culture proven MelioidosisRajeshwari K Muthusamy0Deepak Thangaraju1Sangita S Mehta2Lavanya P3Department of Pathology, KMCH Institute of Health Sciences and Research, Coimbatore, Tamilnadu, IndiaDepartment of Microbiology, KMCH Institute of Health Sciences and Research, Coimbatore, Tamilnadu, IndiaDepartment of Pathology, KMCH Institute of Health Sciences and Research, Coimbatore, Tamilnadu, IndiaDepartment of Pathology, KMCH Institute of Health Sciences and Research, Coimbatore, Tamilnadu, IndiaContext: Melioidosis is a bacterial infection with high morbidity and mortality. Published literature on histopatholgical findings of melioidosis is sparse. Aims: To describe the histopathological findings in melioidosis. Settings and design: This is a retrospective observational study conducted at a tertiary care center in south India. Materials and methods: Histopathological findings of tissue samples from which Burkholderia pseudomallei was isolated in culture were analysed. Statistical analysis: The quantitative variables were expressed as frequency. Results: Histopathological findings in melioidosis were either acute (12 out of 18 samples), acute on chronic (5 out of 18 samples) and chronic (1 out of 18 samples). Granuloma was noted in 5 samples. Conclusion: Any acute or acute on chronic inflammation with or without granuloma in tissues from patients in endemic regions should raise the suspicion of melioidosis. https://natboard.edu.in/ejournal/articledtl?x=bGUvbFlzN2xUTjFPeUY0blVpcFY3Zz09melioidosishistopathologyburkholderia pseudomalleiinflammationgranuloma
spellingShingle Rajeshwari K Muthusamy
Deepak Thangaraju
Sangita S Mehta
Lavanya P
The histopathology of culture proven Melioidosis
National Board of Examinations Journal of Medical Sciences
melioidosis
histopathology
burkholderia pseudomallei
inflammation
granuloma
title The histopathology of culture proven Melioidosis
title_full The histopathology of culture proven Melioidosis
title_fullStr The histopathology of culture proven Melioidosis
title_full_unstemmed The histopathology of culture proven Melioidosis
title_short The histopathology of culture proven Melioidosis
title_sort histopathology of culture proven melioidosis
topic melioidosis
histopathology
burkholderia pseudomallei
inflammation
granuloma
url https://natboard.edu.in/ejournal/articledtl?x=bGUvbFlzN2xUTjFPeUY0blVpcFY3Zz09
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