Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis

Thirty sheep in a flock suffering from fascioliasis were selected for the trial . Clinical findings, hematological, biochemical and fecal investigations were conducted. These animals were equally divided into two groups, the 1st group was given the flukecide triclabendazole alone, at a rate of 12mg/...

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Main Author: Oday K. Luaibi
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2013-12-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/277
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author Oday K. Luaibi
author_facet Oday K. Luaibi
author_sort Oday K. Luaibi
collection DOAJ
description Thirty sheep in a flock suffering from fascioliasis were selected for the trial . Clinical findings, hematological, biochemical and fecal investigations were conducted. These animals were equally divided into two groups, the 1st group was given the flukecide triclabendazole alone, at a rate of 12mg/kg body weight orally and the 2nd group was given the same dose orally together with dexamethasone at a rate 0.5 mg / kg body weight I/M. Results showed that the 2nd group gave the quickest and the best response in the treatment. This could be explained that the use of corticosteroid assisted the triclabendazole in preventing immune damage and fibroplasias inflicted by the liver flukes beside to improvement metabolic actions of the animal.
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spelling doaj.art-69613b29dfd94018b8a10658cb3bbfde2022-12-21T17:50:40ZengUniversity of Baghdad, College of Veterinary MedicineThe Iraqi Journal of Veterinary Medicine1609-56932410-74092013-12-0137210.30539/iraqijvm.v37i2.277Effect of Triclabendazole and Dexamethasone on Ovine FascioliasisOday K. Luaibi01. Department of Veterinary Parasitology, 2. Department of Veterinary Physiology and Pharmacology, 3. Department of Veterinary Internal and Preventive Medicine , College of Veterinary Medicine ,University of Baghdad, 4. Research Center for Cancer and Blood diseases, AL-Mustanseria University, Iraq.Thirty sheep in a flock suffering from fascioliasis were selected for the trial . Clinical findings, hematological, biochemical and fecal investigations were conducted. These animals were equally divided into two groups, the 1st group was given the flukecide triclabendazole alone, at a rate of 12mg/kg body weight orally and the 2nd group was given the same dose orally together with dexamethasone at a rate 0.5 mg / kg body weight I/M. Results showed that the 2nd group gave the quickest and the best response in the treatment. This could be explained that the use of corticosteroid assisted the triclabendazole in preventing immune damage and fibroplasias inflicted by the liver flukes beside to improvement metabolic actions of the animal.https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/277Triclabendazole, Dexamethasone, Fascioliasis, Ovine.
spellingShingle Oday K. Luaibi
Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
The Iraqi Journal of Veterinary Medicine
Triclabendazole, Dexamethasone, Fascioliasis, Ovine.
title Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
title_full Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
title_fullStr Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
title_full_unstemmed Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
title_short Effect of Triclabendazole and Dexamethasone on Ovine Fascioliasis
title_sort effect of triclabendazole and dexamethasone on ovine fascioliasis
topic Triclabendazole, Dexamethasone, Fascioliasis, Ovine.
url https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/277
work_keys_str_mv AT odaykluaibi effectoftriclabendazoleanddexamethasoneonovinefascioliasis