General Approach to Diabetic Neuropathy

Diabetic neuropathy (DN) is the most common complication of diabetes mellitus. It causes microvascular and macrovascular damages and diagnosis can easily be overlooked by most physicians. Generally; the diagnosis of DN can be omitted by physicians dealing with diabetes treatment since it starts with...

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Main Authors: Bora Uzuner, Sertaç Ketenci̇, Ender Salbaş
Format: Article
Language:English
Published: Alanya Alaaddin Keykubat University 2020-10-01
Series:Acta Medica Alanya
Subjects:
Online Access:https://dergipark.org.tr/en/pub/medalanya/issue/57322/788960?publisher=alku
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author Bora Uzuner
Sertaç Ketenci̇
Ender Salbaş
author_facet Bora Uzuner
Sertaç Ketenci̇
Ender Salbaş
author_sort Bora Uzuner
collection DOAJ
description Diabetic neuropathy (DN) is the most common complication of diabetes mellitus. It causes microvascular and macrovascular damages and diagnosis can easily be overlooked by most physicians. Generally; the diagnosis of DN can be omitted by physicians dealing with diabetes treatment since it starts with non-specific findings, shows slow progression and can be confused with complaints in many diseases. It is estimated that there will be 578 million people diagnosed with DN in the world in 2030. Chronic hyperglycemia, microvascular insufficiency, oxidative and nitrosative stress, impaired neurotropism and autoimmunity are some of the factors that cause nerve destruction. Paresthesias such as tingling, burning, electrical shock-like sensations, numbness, throbbing, compression, pinpricks to the skin, complaints are the most common symptoms. There is no treatment for pathogenetic mechanisms in diabetic neuropathy that completely eliminates neuronal damage. The purposes of treatment is slowing down the progression of the disease, controlling the pain, preventing complications, quick and adequate treatment of occurred complications, maintaining the functional capacity of the patient. In this review, we aimed to comprehensively address the general approach to diabetic neuropathy, diagnosis and treatment.
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spelling doaj.art-69630c27a87542f3936ac1e89e6c73f82023-02-15T16:09:00ZengAlanya Alaaddin Keykubat UniversityActa Medica Alanya2587-03192020-10-014329630810.30565/medalanya.788960727General Approach to Diabetic NeuropathyBora UzunerSertaç Ketenci̇Ender Salbaş0NİĞDE T.C. SB. ÖMER HALİSDEMİR ÜNİVERSİTESİ BOR FİZİK TEDAVİ VE REHABİLİTASYON EAH.Diabetic neuropathy (DN) is the most common complication of diabetes mellitus. It causes microvascular and macrovascular damages and diagnosis can easily be overlooked by most physicians. Generally; the diagnosis of DN can be omitted by physicians dealing with diabetes treatment since it starts with non-specific findings, shows slow progression and can be confused with complaints in many diseases. It is estimated that there will be 578 million people diagnosed with DN in the world in 2030. Chronic hyperglycemia, microvascular insufficiency, oxidative and nitrosative stress, impaired neurotropism and autoimmunity are some of the factors that cause nerve destruction. Paresthesias such as tingling, burning, electrical shock-like sensations, numbness, throbbing, compression, pinpricks to the skin, complaints are the most common symptoms. There is no treatment for pathogenetic mechanisms in diabetic neuropathy that completely eliminates neuronal damage. The purposes of treatment is slowing down the progression of the disease, controlling the pain, preventing complications, quick and adequate treatment of occurred complications, maintaining the functional capacity of the patient. In this review, we aimed to comprehensively address the general approach to diabetic neuropathy, diagnosis and treatment.https://dergipark.org.tr/en/pub/medalanya/issue/57322/788960?publisher=alkudiabetes mellitustanıtedavinöropatinöropatik ağrıdiabetes mellitusneuropathic painneuropathydiagnosistreatment
spellingShingle Bora Uzuner
Sertaç Ketenci̇
Ender Salbaş
General Approach to Diabetic Neuropathy
Acta Medica Alanya
diabetes mellitus
tanı
tedavi
nöropati
nöropatik ağrı
diabetes mellitus
neuropathic pain
neuropathy
diagnosis
treatment
title General Approach to Diabetic Neuropathy
title_full General Approach to Diabetic Neuropathy
title_fullStr General Approach to Diabetic Neuropathy
title_full_unstemmed General Approach to Diabetic Neuropathy
title_short General Approach to Diabetic Neuropathy
title_sort general approach to diabetic neuropathy
topic diabetes mellitus
tanı
tedavi
nöropati
nöropatik ağrı
diabetes mellitus
neuropathic pain
neuropathy
diagnosis
treatment
url https://dergipark.org.tr/en/pub/medalanya/issue/57322/788960?publisher=alku
work_keys_str_mv AT borauzuner generalapproachtodiabeticneuropathy
AT sertacketenci generalapproachtodiabeticneuropathy
AT endersalbas generalapproachtodiabeticneuropathy