FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2

FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2

Abstract Background This study investigated the role of Forkhead box Q1 (FOXQ1) in the osteogenic differentiation of bone mesenchymal stem cells. Methods Mouse bone mesenchymal stem cells (mBMSCs) were transfected with lentivirus to generate Foxq1-overexpressing mBMSCs, Foxq1-suppressed mBMSCs, and...

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Bibliographic Details
Main Authors: Lusai Xiang, Junming Zheng, Mengdan Zhang, Tingting Ai, Bin Cai
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Stem Cell Research & Therapy
Subjects:
Forkhead box Q1
Bone mesenchymal stem cells
Osteogenic differentiation
Wnt/β-catenin
Annexin A2
Online Access:http://link.springer.com/article/10.1186/s13287-020-01928-9

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