A Facile One-Pot Process for the Formation of Hindered Tertiary Amines

A Facile One-Pot Process for the Formation of Hindered Tertiary Amines

A simple and convenient method was developed for the preparation of hindered tertiary amines via direct reductive amination of ketones with secondary aryl amines, using trichlorosilane as reducing agent and tetramethylethylenediamine (TMEDA) as organic Lewis base activator. A broad range of ketones...

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Bibliographic Details
Main Authors:	Jian Sun, Chao Wang, Yu Zhang, Zhouyu Wang, Dong Pei
Format:	Article
Language:	English
Published:	MDPI AG 2012-05-01
Series:	Molecules
Subjects:	reductive amination tertiary amine Lewis base trichlorosilane ketone
Online Access:	http://www.mdpi.com/1420-3049/17/5/5151

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