Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture

Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture

Dihydrotestosterone (DHT) is the most potent androgen that regulates hair cycling. Hair cycling involves cross-talk between the androgen and Wnt/β-catenin pathways. However, how DHT regulates hair follicle (HF) growth through the Wnt/β-catenin pathway has not been well investigated. This study aimed...

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Bibliographic Details
Main Authors: Xianyan Chen, Ben Liu, Ying Li, Le Han, Xin Tang, Wenjia Deng, Wei Lai, Miaojian Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
hair follicle
dihydrotestosterone
hair growth
Wnt/β-catenin pathway
β-catenin activator
androgenetic alopecia
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01528/full

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