Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction
Abstract Background Intrauterine growth restriction (IUGR) is a common diagnosis in obstetrics and carries an increased risk of perinatal mortality and morbidity. Identification of IUGR is crucial because proper evaluation and management can result in a favourable outcome. Cardiovascular dysfunction...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-06-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
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| Online Access: | https://doi.org/10.1186/s43055-022-00814-z |
| _version_ | 1811328528928473088 |
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| author | Nesma Saied Ahmed Ahmed Ali Fatma Salah Eldeen Mohammed Ibrahim Nevine AbdelMonem Tawfik Shalaby Hend Galal Eldeen Mohamed Ali Hassan |
| author_facet | Nesma Saied Ahmed Ahmed Ali Fatma Salah Eldeen Mohammed Ibrahim Nevine AbdelMonem Tawfik Shalaby Hend Galal Eldeen Mohamed Ali Hassan |
| author_sort | Nesma Saied Ahmed Ahmed Ali |
| collection | DOAJ |
| description | Abstract Background Intrauterine growth restriction (IUGR) is a common diagnosis in obstetrics and carries an increased risk of perinatal mortality and morbidity. Identification of IUGR is crucial because proper evaluation and management can result in a favourable outcome. Cardiovascular dysfunction and remodelling is a central feature of IUGR. The aim of the study was to use the left modified myocardial performance index (MPI), assess cardiac function in foetuses with intrauterine growth restriction (IUGR) compared to healthy foetuses, and to connect the relationship between changes in MPI and perinatal outcome. A prospective study was conducted with 60 singleton foetuses between 24 and 40 weeks of gestation without foetal chromosomal abnormalities or major malformations, divided into two groups: 30 women with intrauterine growth restriction (30 women) and another 30 women with normal pregnancies (foetal growth pattern appropriate for gestational age and normal heart findings with normal sinus rhythm) who were matched for gestational age and served as the controls. Trans-abdominal ultrasound examination was done with 3.5–7-MHz curvilinear Probe (GE Medical US equipment). The umbilical arteries, middle cerebral artery, and ductus venosus all had blood flow velocity waveforms recorded. The pulsatility index (PI), cerebroplacental ratio (CPR), and Doppler velocimetry (DV) of the umbilical artery were all measured. All foetuses had their myocardial performance index assessed. Normal and abnormal umbilical artery(UA) Doppler, as well as normal and abnormal MCA Doppler, were used to examine the intrauterine growth restriction group. Foetal growth restrictions (FGR) foetuses' Mod-MPI values were compared to gestation-matched controls. The outcomes of the perinatal period were documented. Results Intrauterine growth restriction foetuses with defective umbilical arteries Doppler had a substantially higher mean left myocardial performance index (mean 0.58 SD 0.093) than healthy foetuses (mean 0.45SD 0.070) (P 0.001). When compared to the control group, IUGR foetuses with abnormal left myocardial performance index had a significantly worse perinatal outcome and higher morbidity. When compared to intrauterine growth restriction foetuses with normal MPI, intrauterine growth restriction foetuses with defective left MPI had a significantly worse perinatal outcome (whether the UA Doppler was normal or abnormal). Based on the perinatal result, the foetal myocardial performance index was linked to the severity of foetal impairment in intrauterine growth restriction foetuses. Conclusion MPI has the potential to be a useful technique for evaluating IUGR pregnancies and predicting neonatal outcome. Within the IUGR foetuses, MPI foetal echocardiographic characteristics can define a high-risk group. |
| first_indexed | 2024-04-13T15:27:46Z |
| format | Article |
| id | doaj.art-69664e3178d6436d882eded073fa98c1 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-04-13T15:27:46Z |
| publishDate | 2022-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-69664e3178d6436d882eded073fa98c12022-12-22T02:41:28ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-06-015311910.1186/s43055-022-00814-zRole of prenatal fetal echocardiography in the assessment of intrauterine growth restrictionNesma Saied Ahmed Ahmed Ali0Fatma Salah Eldeen Mohammed Ibrahim1Nevine AbdelMonem Tawfik Shalaby2Hend Galal Eldeen Mohamed Ali Hassan3Diagnostic and Interventional Radiology Department, Faculty of Medicine, Ain Shams UniversityDiagnostic and Interventional Radiology Department, Faculty of Medicine, Ain Shams UniversityDiagnostic and Interventional Radiology Department, Faculty of Medicine, Ain Shams UniversityDiagnostic and Interventional Radiology Department, Faculty of Medicine, Ain Shams UniversityAbstract Background Intrauterine growth restriction (IUGR) is a common diagnosis in obstetrics and carries an increased risk of perinatal mortality and morbidity. Identification of IUGR is crucial because proper evaluation and management can result in a favourable outcome. Cardiovascular dysfunction and remodelling is a central feature of IUGR. The aim of the study was to use the left modified myocardial performance index (MPI), assess cardiac function in foetuses with intrauterine growth restriction (IUGR) compared to healthy foetuses, and to connect the relationship between changes in MPI and perinatal outcome. A prospective study was conducted with 60 singleton foetuses between 24 and 40 weeks of gestation without foetal chromosomal abnormalities or major malformations, divided into two groups: 30 women with intrauterine growth restriction (30 women) and another 30 women with normal pregnancies (foetal growth pattern appropriate for gestational age and normal heart findings with normal sinus rhythm) who were matched for gestational age and served as the controls. Trans-abdominal ultrasound examination was done with 3.5–7-MHz curvilinear Probe (GE Medical US equipment). The umbilical arteries, middle cerebral artery, and ductus venosus all had blood flow velocity waveforms recorded. The pulsatility index (PI), cerebroplacental ratio (CPR), and Doppler velocimetry (DV) of the umbilical artery were all measured. All foetuses had their myocardial performance index assessed. Normal and abnormal umbilical artery(UA) Doppler, as well as normal and abnormal MCA Doppler, were used to examine the intrauterine growth restriction group. Foetal growth restrictions (FGR) foetuses' Mod-MPI values were compared to gestation-matched controls. The outcomes of the perinatal period were documented. Results Intrauterine growth restriction foetuses with defective umbilical arteries Doppler had a substantially higher mean left myocardial performance index (mean 0.58 SD 0.093) than healthy foetuses (mean 0.45SD 0.070) (P 0.001). When compared to the control group, IUGR foetuses with abnormal left myocardial performance index had a significantly worse perinatal outcome and higher morbidity. When compared to intrauterine growth restriction foetuses with normal MPI, intrauterine growth restriction foetuses with defective left MPI had a significantly worse perinatal outcome (whether the UA Doppler was normal or abnormal). Based on the perinatal result, the foetal myocardial performance index was linked to the severity of foetal impairment in intrauterine growth restriction foetuses. Conclusion MPI has the potential to be a useful technique for evaluating IUGR pregnancies and predicting neonatal outcome. Within the IUGR foetuses, MPI foetal echocardiographic characteristics can define a high-risk group.https://doi.org/10.1186/s43055-022-00814-zMyocardial performance indexFoetal echocardiographyMPI, Perinatal outcomeUmbilical artery DopplerIntrauterine growth-restricted foetus |
| spellingShingle | Nesma Saied Ahmed Ahmed Ali Fatma Salah Eldeen Mohammed Ibrahim Nevine AbdelMonem Tawfik Shalaby Hend Galal Eldeen Mohamed Ali Hassan Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction The Egyptian Journal of Radiology and Nuclear Medicine Myocardial performance index Foetal echocardiography MPI, Perinatal outcome Umbilical artery Doppler Intrauterine growth-restricted foetus |
| title | Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction |
| title_full | Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction |
| title_fullStr | Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction |
| title_full_unstemmed | Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction |
| title_short | Role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction |
| title_sort | role of prenatal fetal echocardiography in the assessment of intrauterine growth restriction |
| topic | Myocardial performance index Foetal echocardiography MPI, Perinatal outcome Umbilical artery Doppler Intrauterine growth-restricted foetus |
| url | https://doi.org/10.1186/s43055-022-00814-z |
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