Preparation and Properties of Electrospun PLLA/PTMC Scaffolds
Poly(L-lactide) (PLLA) and PLLA/poly(trimethylene carbonate) (PTMC) scaffolds characterised by different PLLA:PTMC mass ratios (10:0, 9:1, 8:2, 7:3, 6:4 and 5:5) were prepared via electrospinning. The results showed that increasing the PTMC content in the spinning solution caused the following effec...
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MDPI AG
2022-10-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/14/20/4406 |
| _version_ | 1797470149944541184 |
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| author | Dengbang Jiang Haoying Zou Heng Zhang Wan Zhao Yaozhong Lan Mingwei Yuan |
| author_facet | Dengbang Jiang Haoying Zou Heng Zhang Wan Zhao Yaozhong Lan Mingwei Yuan |
| author_sort | Dengbang Jiang |
| collection | DOAJ |
| description | Poly(L-lactide) (PLLA) and PLLA/poly(trimethylene carbonate) (PTMC) scaffolds characterised by different PLLA:PTMC mass ratios (10:0, 9:1, 8:2, 7:3, 6:4 and 5:5) were prepared via electrospinning. The results showed that increasing the PTMC content in the spinning solution caused the following effects: (1) the diameter of the prepared PLLA/PTMC electrospun fibres gradually increased from 188.12 ± 48.87 nm (10:0) to 584.01 ± 60.68 nm (5:5), (2) electrospun fibres with uniform diameters and no beads could be prepared at the PTMC contents of >30%, (3) the elastic modulus of the fibre initially increased and then decreased, reaching a maximum value of 74.49 ± 8.22 Mpa (5:5) and (4) the elongation at the breaking point of the fibres increased gradually from 24.71% to 344.85%. Compared with the PLLA electrospun fibrous membrane, the prepared PLLA/PTMC electrospun fibrous membrane exhibited considerably improved mechanical properties while maintaining good histocompatibility. |
| first_indexed | 2024-03-09T19:32:39Z |
| format | Article |
| id | doaj.art-69672e25c73d44318cf12f7e1828188d |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T19:32:39Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-69672e25c73d44318cf12f7e1828188d2023-11-24T02:08:50ZengMDPI AGPolymers2073-43602022-10-011420440610.3390/polym14204406Preparation and Properties of Electrospun PLLA/PTMC ScaffoldsDengbang Jiang0Haoying Zou1Heng Zhang2Wan Zhao3Yaozhong Lan4Mingwei Yuan5National and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, ChinaNational and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, ChinaNational and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, ChinaNational and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, ChinaNational and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, ChinaNational and Local Joint Engineering Research Center for Green Preparation Technology of Biobased Materials, Yunnan Minzu University, Kunming 650500, ChinaPoly(L-lactide) (PLLA) and PLLA/poly(trimethylene carbonate) (PTMC) scaffolds characterised by different PLLA:PTMC mass ratios (10:0, 9:1, 8:2, 7:3, 6:4 and 5:5) were prepared via electrospinning. The results showed that increasing the PTMC content in the spinning solution caused the following effects: (1) the diameter of the prepared PLLA/PTMC electrospun fibres gradually increased from 188.12 ± 48.87 nm (10:0) to 584.01 ± 60.68 nm (5:5), (2) electrospun fibres with uniform diameters and no beads could be prepared at the PTMC contents of >30%, (3) the elastic modulus of the fibre initially increased and then decreased, reaching a maximum value of 74.49 ± 8.22 Mpa (5:5) and (4) the elongation at the breaking point of the fibres increased gradually from 24.71% to 344.85%. Compared with the PLLA electrospun fibrous membrane, the prepared PLLA/PTMC electrospun fibrous membrane exhibited considerably improved mechanical properties while maintaining good histocompatibility.https://www.mdpi.com/2073-4360/14/20/4406L-polylactic acidpoly(trimethylene carbonate)electrospun fibrestissue engineering |
| spellingShingle | Dengbang Jiang Haoying Zou Heng Zhang Wan Zhao Yaozhong Lan Mingwei Yuan Preparation and Properties of Electrospun PLLA/PTMC Scaffolds Polymers L-polylactic acid poly(trimethylene carbonate) electrospun fibres tissue engineering |
| title | Preparation and Properties of Electrospun PLLA/PTMC Scaffolds |
| title_full | Preparation and Properties of Electrospun PLLA/PTMC Scaffolds |
| title_fullStr | Preparation and Properties of Electrospun PLLA/PTMC Scaffolds |
| title_full_unstemmed | Preparation and Properties of Electrospun PLLA/PTMC Scaffolds |
| title_short | Preparation and Properties of Electrospun PLLA/PTMC Scaffolds |
| title_sort | preparation and properties of electrospun plla ptmc scaffolds |
| topic | L-polylactic acid poly(trimethylene carbonate) electrospun fibres tissue engineering |
| url | https://www.mdpi.com/2073-4360/14/20/4406 |
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