Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors

ABSTRACT Objective: To evaluate the prognosis and influence of associated factors in patients with congenital heart disease admitted for the first time to the Intensive Care Unit of the Hospital da Criança Santo Antônio/Irmandade da Santa Casa de Misericórdia de Porto Alegre, especially those facto...

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Main Authors: Daniélle Bernardi Silveira, Rodrigo da Silva Batisti, Liana Vitória Marchezi, Beatriz Felipe da Rocha, Ernani Bohrer da Rosa, Jamile Dutra Correia, Leonardo Leiria de Moura da Silva, Rafael Fabiano Machado Rosa, Paulo Ricardo Gazzola Zen
Format: Article
Language:English
Published: Sociedade de Pediatria de São Paulo 2024-02-01
Series:Revista Paulista de Pediatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822024000100445&tlng=en
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author Daniélle Bernardi Silveira
Rodrigo da Silva Batisti
Liana Vitória Marchezi
Beatriz Felipe da Rocha
Ernani Bohrer da Rosa
Jamile Dutra Correia
Leonardo Leiria de Moura da Silva
Rafael Fabiano Machado Rosa
Paulo Ricardo Gazzola Zen
author_facet Daniélle Bernardi Silveira
Rodrigo da Silva Batisti
Liana Vitória Marchezi
Beatriz Felipe da Rocha
Ernani Bohrer da Rosa
Jamile Dutra Correia
Leonardo Leiria de Moura da Silva
Rafael Fabiano Machado Rosa
Paulo Ricardo Gazzola Zen
author_sort Daniélle Bernardi Silveira
collection DOAJ
description ABSTRACT Objective: To evaluate the prognosis and influence of associated factors in patients with congenital heart disease admitted for the first time to the Intensive Care Unit of the Hospital da Criança Santo Antônio/Irmandade da Santa Casa de Misericórdia de Porto Alegre, especially those factors associated with death. Methods: Patients were prospectively and consecutively allocated over a period of one year (August 2005 to July 2006). Now, 15 years after the initial selection, we collected data from these patients in the database of the Cytogenetics Laboratory of the Universidade Federal de Ciências da Saúde de Porto Alegre and in the medical records of the hospital. Results: Of the 96 patients, 11 died and 85 were alive until 20 years old. Four patients died in the Intensive Care Unit. The survival probability up to 365 days of life was 95.8%. The survival assessment identified that the deaths occurred mainly before the patients completed one thousand days of life. We found that complex heart disease was independently associated with an odds ratio of 5.19 (95% confidence interval — CI:1.09–24.71; p=0.038) for death. Conclusions: Knowledge about the factors that interfere with the prognosis can be crucial in care practice planning, especially considering that congenital heart disease is an important cause of mortality in the first year of life.
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spelling doaj.art-696791b0ebdb4df2ade5270d7a667dbf2024-02-20T07:37:39ZengSociedade de Pediatria de São PauloRevista Paulista de Pediatria1984-04622024-02-014210.1590/1984-0462/2024/42/2023134Patients' prognosis with congenital heart disease followed by ten years: survival and associated factorsDaniélle Bernardi Silveirahttps://orcid.org/0000-0002-5370-5501Rodrigo da Silva Batistihttps://orcid.org/0000-0003-3268-1333Liana Vitória Marchezihttps://orcid.org/0000-0003-1043-4163Beatriz Felipe da Rochahttps://orcid.org/0009-0003-0337-7620Ernani Bohrer da Rosahttps://orcid.org/0000-0003-4633-0067Jamile Dutra Correiahttps://orcid.org/0000-0002-5802-6890Leonardo Leiria de Moura da Silvahttps://orcid.org/0000-0002-9347-5552Rafael Fabiano Machado Rosahttps://orcid.org/0000-0002-0660-5719Paulo Ricardo Gazzola Zenhttps://orcid.org/0000-0002-7628-4877ABSTRACT Objective: To evaluate the prognosis and influence of associated factors in patients with congenital heart disease admitted for the first time to the Intensive Care Unit of the Hospital da Criança Santo Antônio/Irmandade da Santa Casa de Misericórdia de Porto Alegre, especially those factors associated with death. Methods: Patients were prospectively and consecutively allocated over a period of one year (August 2005 to July 2006). Now, 15 years after the initial selection, we collected data from these patients in the database of the Cytogenetics Laboratory of the Universidade Federal de Ciências da Saúde de Porto Alegre and in the medical records of the hospital. Results: Of the 96 patients, 11 died and 85 were alive until 20 years old. Four patients died in the Intensive Care Unit. The survival probability up to 365 days of life was 95.8%. The survival assessment identified that the deaths occurred mainly before the patients completed one thousand days of life. We found that complex heart disease was independently associated with an odds ratio of 5.19 (95% confidence interval — CI:1.09–24.71; p=0.038) for death. Conclusions: Knowledge about the factors that interfere with the prognosis can be crucial in care practice planning, especially considering that congenital heart disease is an important cause of mortality in the first year of life.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822024000100445&tlng=enCongenital heart defectsInfant mortalityMortalityInfant, newbornRisk factors
spellingShingle Daniélle Bernardi Silveira
Rodrigo da Silva Batisti
Liana Vitória Marchezi
Beatriz Felipe da Rocha
Ernani Bohrer da Rosa
Jamile Dutra Correia
Leonardo Leiria de Moura da Silva
Rafael Fabiano Machado Rosa
Paulo Ricardo Gazzola Zen
Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors
Revista Paulista de Pediatria
Congenital heart defects
Infant mortality
Mortality
Infant, newborn
Risk factors
title Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors
title_full Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors
title_fullStr Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors
title_full_unstemmed Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors
title_short Patients' prognosis with congenital heart disease followed by ten years: survival and associated factors
title_sort patients prognosis with congenital heart disease followed by ten years survival and associated factors
topic Congenital heart defects
Infant mortality
Mortality
Infant, newborn
Risk factors
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822024000100445&tlng=en
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