PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells
Summary: MSI2, which is expressed predominantly in hematopoietic stem and progenitor cells (HSPCs), enforces HSPC expansion when overexpressed and is upregulated in myeloid leukemias, indicating its regulated transcription is critical to balanced self-renewal and leukemia restraint. Despite this, li...
Main Authors: | Muluken S. Belew, Sonam Bhatia, Ava Keyvani Chahi, Stefan Rentas, Jonathan S. Draper, Kristin J. Hope |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-04-01
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Series: | Stem Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213671118301334 |
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