Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device
Acute right heart failure is associated with impaired prognosis in cardiogenic shock. Since most pharmacological therapies are not evaluated for the failing right ventricle, or even contraindicated, there is a need for rapid minimal invasive circulatory right heart support. The PERKAT RV is such a d...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-01-01
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| Series: | Therapeutic Advances in Cardiovascular Disease |
| Online Access: | https://doi.org/10.1177/1753944719895902 |
| _version_ | 1811224311901454336 |
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| author | Markus W. Ferrari P. Christian Schulze Daniel Kretzschmar |
| author_facet | Markus W. Ferrari P. Christian Schulze Daniel Kretzschmar |
| author_sort | Markus W. Ferrari |
| collection | DOAJ |
| description | Acute right heart failure is associated with impaired prognosis in cardiogenic shock. Since most pharmacological therapies are not evaluated for the failing right ventricle, or even contraindicated, there is a need for rapid minimal invasive circulatory right heart support. The PERKAT RV is such a device for acute therapy in congestive heart failure. It reduces the central venous pooling by pumping blood from the inferior vena cava into the pulmonary artery with flow rates of up to 4 litres/min. The device was evaluated in an animal model of acute pulmonary embolism after careful in vitro tests. PERKAT RV increased cardiac output by 59% in sheep suffering from acute right heart failure. We await the first human implantation in the near future. Based on the PERKAT concept, future devolvement will also focus on left heart support. |
| first_indexed | 2024-04-12T08:47:17Z |
| format | Article |
| id | doaj.art-696f08fa60b84b07982a4e4882d1c372 |
| institution | Directory Open Access Journal |
| issn | 1753-9455 |
| language | English |
| last_indexed | 2024-04-12T08:47:17Z |
| publishDate | 2020-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Cardiovascular Disease |
| spelling | doaj.art-696f08fa60b84b07982a4e4882d1c3722022-12-22T03:39:40ZengSAGE PublishingTherapeutic Advances in Cardiovascular Disease1753-94552020-01-011410.1177/1753944719895902Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support deviceMarkus W. FerrariP. Christian SchulzeDaniel KretzschmarAcute right heart failure is associated with impaired prognosis in cardiogenic shock. Since most pharmacological therapies are not evaluated for the failing right ventricle, or even contraindicated, there is a need for rapid minimal invasive circulatory right heart support. The PERKAT RV is such a device for acute therapy in congestive heart failure. It reduces the central venous pooling by pumping blood from the inferior vena cava into the pulmonary artery with flow rates of up to 4 litres/min. The device was evaluated in an animal model of acute pulmonary embolism after careful in vitro tests. PERKAT RV increased cardiac output by 59% in sheep suffering from acute right heart failure. We await the first human implantation in the near future. Based on the PERKAT concept, future devolvement will also focus on left heart support.https://doi.org/10.1177/1753944719895902 |
| spellingShingle | Markus W. Ferrari P. Christian Schulze Daniel Kretzschmar Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device Therapeutic Advances in Cardiovascular Disease |
| title | Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device |
| title_full | Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device |
| title_fullStr | Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device |
| title_full_unstemmed | Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device |
| title_short | Acute right heart failure: future perspective with the PERKAT RV pulsatile right ventricular support device |
| title_sort | acute right heart failure future perspective with the perkat rv pulsatile right ventricular support device |
| url | https://doi.org/10.1177/1753944719895902 |
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