A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore
Objective The objective of this study was to study relation of ß-thalassemia and its types (major, minor, intermedia) with ABO and Rh blood groups in Lahore, Pakistan. Materials and methods It was an observational study, in which ABO and Rh blood grouping of 711 β-Thalassemia patients was...
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Format: | Article |
Language: | English |
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University of Management and Technology
2023-06-01
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Series: | Bioscientific Review |
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Online Access: | https://journals.umt.edu.pk/index.php/BSR/article/view/2735 |
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author | Kainat Waheed Syed Muhammad Ammad Rizvi Bushra Mubarak |
author_facet | Kainat Waheed Syed Muhammad Ammad Rizvi Bushra Mubarak |
author_sort | Kainat Waheed |
collection | DOAJ |
description |
Objective
The objective of this study was to study relation of ß-thalassemia and its types (major, minor, intermedia) with ABO and Rh blood groups in Lahore, Pakistan.
Materials and methods
It was an observational study, in which ABO and Rh blood grouping of 711 β-Thalassemia patients was performed, after taking consent from patients. Blood grouping was performed by forward and reverse grouping, using tube method.
Results
The observed ABO blood group pattern, in both genders was O>B>A>AB. The overall frequency of O and A blood group was higher in female patients while frequency of B and AB was higher in male patients, but the difference was non-significant. Significant difference was observed between gender and Rh factor. Most patients of β-thalassemia lies in the category of major 48%, followed by minor 44% and intermedia 8%. Overall patients of AB blood group are mostly the patients of β-thalassemia major while β-thalassemia minor and intermedia had highest frequency of blood group B.
Conclusion
It was concluded from the study that the patients of ß-thalassemia have higher frequency of O+ blood group and least frequency of AB- blood group. A significant difference was seen in Rh blood group between the male and female patients. There was no significant difference (p > 0.05) in distribution of ABO and Rh blood group according to type of β-thalassemia.
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first_indexed | 2024-03-13T02:54:29Z |
format | Article |
id | doaj.art-696f754b46e346d9961563e3b775cfd9 |
institution | Directory Open Access Journal |
issn | 2663-4198 2663-4201 |
language | English |
last_indexed | 2024-03-13T02:54:29Z |
publishDate | 2023-06-01 |
publisher | University of Management and Technology |
record_format | Article |
series | Bioscientific Review |
spelling | doaj.art-696f754b46e346d9961563e3b775cfd92023-06-28T06:38:07ZengUniversity of Management and TechnologyBioscientific Review2663-41982663-42012023-06-0152A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in LahoreKainat Waheed0Syed Muhammad Ammad Rizvi1Bushra Mubarak2{'en_US': 'The University of Lahore'}The University of LahoreThe University of Lahore Objective The objective of this study was to study relation of ß-thalassemia and its types (major, minor, intermedia) with ABO and Rh blood groups in Lahore, Pakistan. Materials and methods It was an observational study, in which ABO and Rh blood grouping of 711 β-Thalassemia patients was performed, after taking consent from patients. Blood grouping was performed by forward and reverse grouping, using tube method. Results The observed ABO blood group pattern, in both genders was O>B>A>AB. The overall frequency of O and A blood group was higher in female patients while frequency of B and AB was higher in male patients, but the difference was non-significant. Significant difference was observed between gender and Rh factor. Most patients of β-thalassemia lies in the category of major 48%, followed by minor 44% and intermedia 8%. Overall patients of AB blood group are mostly the patients of β-thalassemia major while β-thalassemia minor and intermedia had highest frequency of blood group B. Conclusion It was concluded from the study that the patients of ß-thalassemia have higher frequency of O+ blood group and least frequency of AB- blood group. A significant difference was seen in Rh blood group between the male and female patients. There was no significant difference (p > 0.05) in distribution of ABO and Rh blood group according to type of β-thalassemia. https://journals.umt.edu.pk/index.php/BSR/article/view/2735β Thalassemia, Blood groups, Haemoglobin, Iron overload |
spellingShingle | Kainat Waheed Syed Muhammad Ammad Rizvi Bushra Mubarak A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore Bioscientific Review β Thalassemia, Blood groups, Haemoglobin, Iron overload |
title | A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore |
title_full | A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore |
title_fullStr | A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore |
title_full_unstemmed | A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore |
title_short | A descriptive study on association of β Thalassemia and its types with ABO & Rh blood groups, in Lahore |
title_sort | descriptive study on association of β thalassemia and its types with abo rh blood groups in lahore |
topic | β Thalassemia, Blood groups, Haemoglobin, Iron overload |
url | https://journals.umt.edu.pk/index.php/BSR/article/view/2735 |
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