Montelukast induces beneficial behavioral outcomes and reduces inflammation in male and female rats

Montelukast induces beneficial behavioral outcomes and reduces inflammation in male and female rats

BackgroundAccumulative data links inflammation and immune dysregulation to the pathophysiology of mental disorders; little is known regarding leukotrienes’ (LTs) involvement in this process. Circumstantial evidence suggests that treatment with leukotriene modifying agents (LTMAs) such as montelukast...

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Bibliographic Details
Main Authors: Ira S. Rostevanov, Batya Betesh-Abay, Ahmad Nassar, Elina Rubin, Sarit Uzzan, Jacob Kaplanski, Linoy Biton, Abed N. Azab
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
behavior
depression
inflammation
leukotrienes
mania
mental disorders
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.981440/full

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