Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience

Apolipoprotein epsilon 3 alleles are associated with indicators of neuronal resilience

<p>Abstract</p> <p>Background</p> <p>Epilepsy is associated with precocious development of Alzheimer-type neuropathological changes, including appearance of senile plaques, neuronal loss and glial activation. As inheritance of <it>APOE ε4 </it>allele(s) is r...

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Bibliographic Details
Main Authors: Aboud Orwa, Mrak Robert E, Boop Frederick, Griffin Sue T
Format: Article
Language:English
Published: BMC 2012-04-01
Series:BMC Medicine
Subjects:
Amyloid beta (Aβ)
Alzheimer disease
<it>APOE </it>genotype
DNA damage
epilepsy
interleukin-1
neuroinflammation
phosphorylated tau
synaptophysin
TUNEL
Online Access:http://www.biomedcentral.com/1741-7015/10/35

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