An Outbreak of Bartonella bacilliformis in an Endemic Andean Community.
BACKGROUND:Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. METHODS:Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003). RESULTS:The majority of cases (65%) w...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4798250?pdf=render |
| _version_ | 1818133816635555840 |
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| author | Nuria Sanchez Clemente Cesar Ugarte-Gil Nelson Solorzano Ciro Maguiña David Moore |
| author_facet | Nuria Sanchez Clemente Cesar Ugarte-Gil Nelson Solorzano Ciro Maguiña David Moore |
| author_sort | Nuria Sanchez Clemente |
| collection | DOAJ |
| description | BACKGROUND:Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. METHODS:Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003). RESULTS:The majority of cases (65%) were 14 years old and younger. There was a peak in acute cases after the rainy season; chronic cases presented more constantly throughout the year. The sensitivity of blood smear against blood culture in acute disease was 25%. The most commonly used treatment for chronic disease was rifampicin; chloramphenicol was used to treat most acute cases. Complications arose in 6.8% and there were no deaths. CONCLUSIONS:Diagnostic and treatment algorithms for acute and chronic bartonellosis have been developed without a strong evidence base. Preparation of ready-to-go operational research protocols for future outbreaks would strengthen the evidence base for diagnostic and treatment strategies and enhance opportunities for control. |
| first_indexed | 2024-12-11T08:58:44Z |
| format | Article |
| id | doaj.art-69733da0501740ce908b0de846586054 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-11T08:58:44Z |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-69733da0501740ce908b0de8465860542022-12-22T01:13:49ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01113e015052510.1371/journal.pone.0150525An Outbreak of Bartonella bacilliformis in an Endemic Andean Community.Nuria Sanchez ClementeCesar Ugarte-GilNelson SolorzanoCiro MaguiñaDavid MooreBACKGROUND:Bartonellosis affects small Andean communities in Peru, Colombia and Ecuador. Research in this area has been limited. METHODS:Retrospective review of 191 cases of bartonellosis managed in Caraz District Hospital, Peru, during the last outbreak (2003). RESULTS:The majority of cases (65%) were 14 years old and younger. There was a peak in acute cases after the rainy season; chronic cases presented more constantly throughout the year. The sensitivity of blood smear against blood culture in acute disease was 25%. The most commonly used treatment for chronic disease was rifampicin; chloramphenicol was used to treat most acute cases. Complications arose in 6.8% and there were no deaths. CONCLUSIONS:Diagnostic and treatment algorithms for acute and chronic bartonellosis have been developed without a strong evidence base. Preparation of ready-to-go operational research protocols for future outbreaks would strengthen the evidence base for diagnostic and treatment strategies and enhance opportunities for control.http://europepmc.org/articles/PMC4798250?pdf=render |
| spellingShingle | Nuria Sanchez Clemente Cesar Ugarte-Gil Nelson Solorzano Ciro Maguiña David Moore An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. PLoS ONE |
| title | An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. |
| title_full | An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. |
| title_fullStr | An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. |
| title_full_unstemmed | An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. |
| title_short | An Outbreak of Bartonella bacilliformis in an Endemic Andean Community. |
| title_sort | outbreak of bartonella bacilliformis in an endemic andean community |
| url | http://europepmc.org/articles/PMC4798250?pdf=render |
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