Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review
Atypical polypoid adenomyoma (APAM) is a rare polypoid benign tumor of the uterus that causes irregular vaginal bleeding in women of reproductive age. It has the potential for malignant transformation, but it does not metastasize. APAM may coexist with endometrial hyperplasia and adenocarcinoma, usu...
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MDPI AG
2023-12-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/12/2352 |
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| author | Tudor Butureanu Ana-Maria Haliciu Ana-Maria Apetrei Ioana Pavaleanu Razvan Vladimir Socolov Raluca Anca Balan |
| author_facet | Tudor Butureanu Ana-Maria Haliciu Ana-Maria Apetrei Ioana Pavaleanu Razvan Vladimir Socolov Raluca Anca Balan |
| author_sort | Tudor Butureanu |
| collection | DOAJ |
| description | Atypical polypoid adenomyoma (APAM) is a rare polypoid benign tumor of the uterus that causes irregular vaginal bleeding in women of reproductive age. It has the potential for malignant transformation, but it does not metastasize. APAM may coexist with endometrial hyperplasia and adenocarcinoma, usually leading to misdiagnosis. Histopathologically, it is a biphasic tumor, represented by the endometrioid glands with a complex histoarchitecture, with sometimes squamous morular metaplasia or cytologic atypia, interspersed with a fibromyomatous stroma. This tumor has a high incidence of recurrence. We present a very rare case of a 21-year-old patient, a virgin, without a significant medical history, with a bleeding mass occupying the vagina. The mass was excised using forceps, scissors, and a suture of the visible pedicle. After a four-year follow-up and no additional medical treatment, no relapse was observed. Given the risk of recurrence and progression, APAM might be treated via a hysterectomy in patients with no desire for pregnancy. Due to a lower recurrence rate, the conservative treatment of atypical polypoid adenomyoma performed via an operative hysteroscopy represents the best choice. Previously diagnosed in hysterectomy specimens, with the introduction of better-performing indirect imaging techniques, adenomyosis is a clinical entity that has the possibility of being diagnosed in the presurgical stage. |
| first_indexed | 2024-03-08T20:35:49Z |
| format | Article |
| id | doaj.art-69736a5a39d449c7901a49b266ce8805 |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-08T20:35:49Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-69736a5a39d449c7901a49b266ce88052023-12-22T14:21:24ZengMDPI AGLife2075-17292023-12-011312235210.3390/life13122352Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature ReviewTudor Butureanu0Ana-Maria Haliciu1Ana-Maria Apetrei2Ioana Pavaleanu3Razvan Vladimir Socolov4Raluca Anca Balan5Department of Mother and Child, “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Mother and Child, “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Mother and Child, “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Mother and Child, “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, RomaniaDepartment of Mother and Child, “Gr. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania“Elena Doamna” University Hospital of Obstetrics and Gynecology, 49, Elena Doamna St., 700398 Iasi, RomaniaAtypical polypoid adenomyoma (APAM) is a rare polypoid benign tumor of the uterus that causes irregular vaginal bleeding in women of reproductive age. It has the potential for malignant transformation, but it does not metastasize. APAM may coexist with endometrial hyperplasia and adenocarcinoma, usually leading to misdiagnosis. Histopathologically, it is a biphasic tumor, represented by the endometrioid glands with a complex histoarchitecture, with sometimes squamous morular metaplasia or cytologic atypia, interspersed with a fibromyomatous stroma. This tumor has a high incidence of recurrence. We present a very rare case of a 21-year-old patient, a virgin, without a significant medical history, with a bleeding mass occupying the vagina. The mass was excised using forceps, scissors, and a suture of the visible pedicle. After a four-year follow-up and no additional medical treatment, no relapse was observed. Given the risk of recurrence and progression, APAM might be treated via a hysterectomy in patients with no desire for pregnancy. Due to a lower recurrence rate, the conservative treatment of atypical polypoid adenomyoma performed via an operative hysteroscopy represents the best choice. Previously diagnosed in hysterectomy specimens, with the introduction of better-performing indirect imaging techniques, adenomyosis is a clinical entity that has the possibility of being diagnosed in the presurgical stage.https://www.mdpi.com/2075-1729/13/12/2352adenomyosispolypoidendometriosiscervicalmalignantpolyp |
| spellingShingle | Tudor Butureanu Ana-Maria Haliciu Ana-Maria Apetrei Ioana Pavaleanu Razvan Vladimir Socolov Raluca Anca Balan Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review Life adenomyosis polypoid endometriosis cervical malignant polyp |
| title | Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review |
| title_full | Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review |
| title_fullStr | Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review |
| title_full_unstemmed | Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review |
| title_short | Prolapsed Atypical Polypoid Adenomyoma—A Case Report and Literature Review |
| title_sort | prolapsed atypical polypoid adenomyoma a case report and literature review |
| topic | adenomyosis polypoid endometriosis cervical malignant polyp |
| url | https://www.mdpi.com/2075-1729/13/12/2352 |
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