Inadequate timing between corticosteroid and antibiotics applications increases mortality due to sepsis

Inadequate timing between corticosteroid and antibiotics applications increases mortality due to sepsis

This study tested the hypothesis that the use of corticosteroids prior to antibiotics can lower the mortality rate in severe infections by S. aureus or Gram-negative bacilli, using an animal model. This study was a prospective and controlled study, placed in a university laboratory. Seven hundred an...

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Bibliographic Details
Main Authors: Marcus Vinícius Telles Fadel, João Carlos Repka, Cláudio Leinig Pereira da Cunha, Maria Terezinha C. Leão
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Adrenal cortex hormones
antibiotics
sepsis
survival
mice
animals
laboratory
severe infection
peritonitis
shock
endotoxin
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500013&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000500013&lng=en&tlng=en

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