circKIF4A promotes tumorogenesis of glioma by targeting miR-139-3p to activate Wnt5a signaling

circKIF4A promotes tumorogenesis of glioma by targeting miR-139-3p to activate Wnt5a signaling

Abstract Background Glioma has the characteristics of high incidence and mortality, and is a common malignant tumor of the central nervous system. Circular RNAs (circRNAs) have been reported to play vital roles in progression of cancer including glioma, and circKIF4A is up-regulated in glioma tissue...

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Bibliographic Details
Main Authors: Long-Wei Huo, Ya-Fei Wang, Xiao-Bin Bai, Hu-Lin Zheng, Mao-De Wang
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Molecular Medicine
Subjects:
circKIF4A
Glioma
miR-139-3p
Wnt5a
Proliferation
Migration
Online Access:http://link.springer.com/article/10.1186/s10020-020-00159-1

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