Encoding and Decoding of p53 Dynamics in Cellular Response to Stresses

In the cellular response to stresses, the tumor suppressor p53 is activated to maintain genomic integrity and fidelity. As a transcription factor, p53 exhibits rich dynamics to allow for discrimination of the type and intensity of stresses and to direct the selective activation of target genes invol...

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Bibliographic Details
Main Authors: Ping Wang, Hang-Yu Wang, Xing-Jie Gao, Hua-Xia Zhu, Xiao-Peng Zhang, Feng Liu, Wei Wang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/3/490