Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55
In his recent review for the Journal of Cardiovascular Development and Disease, Cirillo offers a concept for “cardiac memory” based on the notion that the ventricular cone can be unwrapped to show a myocardial band extending from the pulmonary to the aortic root. The concept of the myocardial band w...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2018-12-01
|
| Series: | Journal of Cardiovascular Development and Disease |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2308-3425/5/4/60 |
| _version_ | 1819178262287351808 |
|---|---|
| author | Robert H. Anderson |
| author_facet | Robert H. Anderson |
| author_sort | Robert H. Anderson |
| collection | DOAJ |
| description | In his recent review for the Journal of Cardiovascular Development and Disease, Cirillo offers a concept for “cardiac memory” based on the notion that the ventricular cone can be unwrapped to show a myocardial band extending from the pulmonary to the aortic root. The concept of the myocardial band was itself developed by Torrent Guasp, and has subsequently been championed by Buckberg. Neither Torrent Guasp, when formulating his initial concept, nor Buckberg in his subsequent endorsements, have validated the results of dissection using histological or other techniques that would reveal the boundaries of the alleged band. In contrast, there is a wealth of evidence showing that such boundaries do not exist and that the cardiomyocytes are packed together within the walls of the ventricular cone in the form of a three-dimensional mesh. The evidence demonstrating the manner of packing of the cardiomyocytes within the ventricular walls was summarised in another recent review published in the journal. It is disappointing that Cirillo chose to ignore the wealth of evidence disproving the concept on which he bases his entire review. Only by recognising the existence of this evidence can we truly understand ventricular function correctly, as envisaged by Cirillo. |
| first_indexed | 2024-12-22T21:39:45Z |
| format | Article |
| id | doaj.art-697c7c6c7ad54b52a0ee0d5772b0f635 |
| institution | Directory Open Access Journal |
| issn | 2308-3425 |
| language | English |
| last_indexed | 2024-12-22T21:39:45Z |
| publishDate | 2018-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Cardiovascular Development and Disease |
| spelling | doaj.art-697c7c6c7ad54b52a0ee0d5772b0f6352022-12-21T18:11:39ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252018-12-01546010.3390/jcdd5040060jcdd5040060Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55Robert H. Anderson0Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne NE1 4EP, UKIn his recent review for the Journal of Cardiovascular Development and Disease, Cirillo offers a concept for “cardiac memory” based on the notion that the ventricular cone can be unwrapped to show a myocardial band extending from the pulmonary to the aortic root. The concept of the myocardial band was itself developed by Torrent Guasp, and has subsequently been championed by Buckberg. Neither Torrent Guasp, when formulating his initial concept, nor Buckberg in his subsequent endorsements, have validated the results of dissection using histological or other techniques that would reveal the boundaries of the alleged band. In contrast, there is a wealth of evidence showing that such boundaries do not exist and that the cardiomyocytes are packed together within the walls of the ventricular cone in the form of a three-dimensional mesh. The evidence demonstrating the manner of packing of the cardiomyocytes within the ventricular walls was summarised in another recent review published in the journal. It is disappointing that Cirillo chose to ignore the wealth of evidence disproving the concept on which he bases his entire review. Only by recognising the existence of this evidence can we truly understand ventricular function correctly, as envisaged by Cirillo.https://www.mdpi.com/2308-3425/5/4/60anatomydevelopmenthelical heartthree-dimensional meshventricular mural architecture |
| spellingShingle | Robert H. Anderson Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55 Journal of Cardiovascular Development and Disease anatomy development helical heart three-dimensional mesh ventricular mural architecture |
| title | Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55 |
| title_full | Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55 |
| title_fullStr | Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55 |
| title_full_unstemmed | Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55 |
| title_short | Comment on “The Memory of the Heart”, <em>J. Cardiovasc. Dev. Dis.</em> 2018, 5, 55 |
| title_sort | comment on the memory of the heart em j cardiovasc dev dis em 2018 5 55 |
| topic | anatomy development helical heart three-dimensional mesh ventricular mural architecture |
| url | https://www.mdpi.com/2308-3425/5/4/60 |
| work_keys_str_mv | AT roberthanderson commentonthememoryoftheheartemjcardiovascdevdisem2018555 |