<i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications
<i>Psidium guajava</i> L. (guava) is a small tree known for its fruit flavor that is cultivated almost around the globe in tropical areas. Its fruit is amazingly rich in antioxidants, vitamin C, potassium, and dietary fiber. In different parts of the world, this plant holds a special pla...
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| Format: | Article |
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MDPI AG
2022-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/20/7016 |
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| author | Muhammad Imran Tousif Mamona Nazir Muhammad Saleem Saba Tauseef Nusrat Shafiq Laiba Hassan Hidayat Hussian Domenico Montesano Daniele Naviglio Gokhan Zengin Ishtiaq Ahmad |
| author_facet | Muhammad Imran Tousif Mamona Nazir Muhammad Saleem Saba Tauseef Nusrat Shafiq Laiba Hassan Hidayat Hussian Domenico Montesano Daniele Naviglio Gokhan Zengin Ishtiaq Ahmad |
| author_sort | Muhammad Imran Tousif |
| collection | DOAJ |
| description | <i>Psidium guajava</i> L. (guava) is a small tree known for its fruit flavor that is cultivated almost around the globe in tropical areas. Its fruit is amazingly rich in antioxidants, vitamin C, potassium, and dietary fiber. In different parts of the world, this plant holds a special place with respect to fruit and nutritional items. Pharmacological research has shown that this plant has more potential than just a fruit source; it also has beneficial effects against a variety of chronic diseases due to its rich nutritional and phytochemical profile. The primary goal of this document is to provide an updated overview of <i>Psidium guajava</i> L. and its bioactive secondary metabolites, as well as their availability for further study, with a focus on the health benefits and potential industrial applications. There have been several studies conducted on <i>Psidium guajava</i> L. in relation to its use in the pharmaceutical industry. However, its clinical efficacy and applications are still debatable. Therefore, in this review a detailed study with respect to phytochemistry of the plant through modern instruments such as GC and LC-MS has been discussed. The biological activities of secondary metabolites isolated from this plant have been extensively discussed. In order to perform long-term clinical trials to learn more about their effectiveness as drugs and applications for various health benefits, a structure activity relationship has been established. Based on the literature, it is concluded that this plant has a wide variety of biopharmaceutical applications. As a whole, this article calls for long-term clinical trials to obtain a greater understanding of how it can be used to treat different diseases. |
| first_indexed | 2024-03-09T19:41:23Z |
| format | Article |
| id | doaj.art-69815d97185c47c5be238c512308e37d |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T19:41:23Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-69815d97185c47c5be238c512308e37d2023-11-24T01:35:40ZengMDPI AGMolecules1420-30492022-10-012720701610.3390/molecules27207016<i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial ApplicationsMuhammad Imran Tousif0Mamona Nazir1Muhammad Saleem2Saba Tauseef3Nusrat Shafiq4Laiba Hassan5Hidayat Hussian6Domenico Montesano7Daniele Naviglio8Gokhan Zengin9Ishtiaq Ahmad10Department of Chemistry, Division of Science and Technology, University of Education, Lahore 54000, PakistanDepartment of Chemistry, Govt. Sadiq College Women University Bahawalpur, Bahawalpur 63100, PakistanDivision of Organic Chemistry, Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, PakistanDr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, PakistanDepartment of Chemistry, Government College Women University Faisalabad, Faisalabad 38000, PakistanDepartment of Pharmacy, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur 63100, PakistanDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, D-06120 Halle, GermanyDepartment of Pharmacy, University of Naples Federico II, Via D. Montesano 49, 80131 Naples, ItalyDepartment of Chemical Sciences, University of Naples Federico II, Via Cintia, 4, 80126 Naples, ItalyDepartment of Biology, Science Faculty, Selcuk University, Konya 42130, TurkeyDepartment of Chemical Engineering and Biotechnology, University of Cambridge, Philipa Fawcett Drive, Cambridge CB3 0AS, UK<i>Psidium guajava</i> L. (guava) is a small tree known for its fruit flavor that is cultivated almost around the globe in tropical areas. Its fruit is amazingly rich in antioxidants, vitamin C, potassium, and dietary fiber. In different parts of the world, this plant holds a special place with respect to fruit and nutritional items. Pharmacological research has shown that this plant has more potential than just a fruit source; it also has beneficial effects against a variety of chronic diseases due to its rich nutritional and phytochemical profile. The primary goal of this document is to provide an updated overview of <i>Psidium guajava</i> L. and its bioactive secondary metabolites, as well as their availability for further study, with a focus on the health benefits and potential industrial applications. There have been several studies conducted on <i>Psidium guajava</i> L. in relation to its use in the pharmaceutical industry. However, its clinical efficacy and applications are still debatable. Therefore, in this review a detailed study with respect to phytochemistry of the plant through modern instruments such as GC and LC-MS has been discussed. The biological activities of secondary metabolites isolated from this plant have been extensively discussed. In order to perform long-term clinical trials to learn more about their effectiveness as drugs and applications for various health benefits, a structure activity relationship has been established. Based on the literature, it is concluded that this plant has a wide variety of biopharmaceutical applications. As a whole, this article calls for long-term clinical trials to obtain a greater understanding of how it can be used to treat different diseases.https://www.mdpi.com/1420-3049/27/20/7016<i>Psidium guajava</i> L.phytochemistrymeroterpenoidpharmacological activitiesindustrial application |
| spellingShingle | Muhammad Imran Tousif Mamona Nazir Muhammad Saleem Saba Tauseef Nusrat Shafiq Laiba Hassan Hidayat Hussian Domenico Montesano Daniele Naviglio Gokhan Zengin Ishtiaq Ahmad <i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications Molecules <i>Psidium guajava</i> L. phytochemistry meroterpenoid pharmacological activities industrial application |
| title | <i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications |
| title_full | <i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications |
| title_fullStr | <i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications |
| title_full_unstemmed | <i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications |
| title_short | <i>Psidium guajava</i> L. An Incalculable but Underexplored Food Crop: Its Phytochemistry, Ethnopharmacology, and Industrial Applications |
| title_sort | i psidium guajava i l an incalculable but underexplored food crop its phytochemistry ethnopharmacology and industrial applications |
| topic | <i>Psidium guajava</i> L. phytochemistry meroterpenoid pharmacological activities industrial application |
| url | https://www.mdpi.com/1420-3049/27/20/7016 |
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