Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex.

Voxelized simulation of cerebral oxygen perfusion elucidates hypoxia in aged mouse cortex.

Departures of normal blood flow and metabolite distribution from the cerebral microvasculature into neuronal tissue have been implicated with age-related neurodegeneration. Mathematical models informed by spatially and temporally distributed neuroimage data are becoming instrumental for reconstructi...

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Bibliographic Details
Main Authors:	Grant Hartung, Shoale Badr, Mohammad Moeini, Frédéric Lesage, David Kleinfeld, Ali Alaraj, Andreas Linninger
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2021-01-01
Series:	PLoS Computational Biology
Online Access:	https://doi.org/10.1371/journal.pcbi.1008584

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